Updated August 2010

2008/2007        2006/2005        2004/2003        2002/2001        2000/1999

1998/1997        1996/1995        1994/1993        1992/1991

350. Uphoff CC, Drexler HG: Mycoplasma contamination of cell cultures. in: The Encyclopedia of Industrial Biotechnology, Bioprocess, Bioseparation and Cell Technology, Vol. 5 (ed Flickinger MC), Wiley, New York (2010), pp. 3611-3630.

349. Ernst T, Chase AJ, Score J, Hidalgo-Curtis CE, Bryant C, Jones A, Waghorn K, Zoi K, Ross F, Reiter A, Hochhaus A, Drexler HG, Duncombe A, Cervantes F, Oscier D, Boultwood J, Grand FH, Cross NCP: Inactivating mutations of the histone methyltransferase EZH2 in myeloid disorders. Nature Genetics 42: 722-727 (2010). PubMedID 20601953

348. Nagel S, Venturini L, Marquez VE, Meyer C, Kaufmann M, Scheer M, MacLeod RAF, Drexler HG: Polycomb repressor complex 2 regulates HOXA9 and HOXA10, activating ID2 in NK/T-cell lines. Mol Cancer 9: 151 (2010). PubMedID 20565746

347. Schneider B, Drexler HG, MacLeod RAF: Deep insight - LDI-PCR in translocation analysis. Atlas of Genetics and Cytogenetics in Oncology and Haematology, June 2010.
URL: http://atlasgeneticsoncology.org/Deep/LDI-PCRinCancerID20087.html

346. Alston-Roberts C, Barallon R, Bauer SR, Butler J, Capes-Davis A, Dirks WG, Elmore E, Furtado M, Kerrigan L, Kline MC, Kohara A, Los GV, MacLeod RAF, Masters JR, Nardone M, Nims RW, Price PJ, Reid YA, Shewale J, Steuer AF, Storts DR, Sykes G, Taraporewala Z, Thomson J: Cell line misidentification: the beginning of the end. Nat Rev Cancer 10: 441-448 (2010). PubMedID 20448633

345. Nagel S, Leich E, Quentmeier H, Meyer C, Kaufmann M, Zaborski M, Rosenwald A, Drexler HG, MacLeod RAF: Amplification at 11q23 targets protein kinase SIK2 in diffuse large B-cell lymphoma. Leukemia Lymphoma 51: 881-891 (2010). PubMedID 20367563

344. Capes-Davis A, Theodosopoulos G, Atkin I, Drexler HG, Kohara A, MacLeod RAF, Masters JR, Nakamura Y, Reid YA, Reddel RR, Freshney RA: Check your cultures! A list of cross-contaminated or misidentified cell lines. Int J Cancer 127: 1-8 (2010). PubMedID 20143388

343. Uphoff CC, Denkmann SA, Steube KG, Drexler HG: Detection of EBV, HBV, HCV, HIV-1, HTLV-I and -II and SMRV in human and other primate cell lines. J Biomed Biotechnol, Vol. 2010: Article ID 904767, 23 pages (2010). PubMedID 20454443

342. Drexler HG: Guide to Leukemia-Lymphoma Cell Lines, 2nd Edition. Braunschweig, 2010, eBook CD, 898 pages.

341. Dittmar KEJ, Simann M, Zghoul N, Schön O, Meyring W, Hannig H, Macke L, Dirks WG, Miller K, Garritsen HSP, Lindenmaier W: Quality of cell products: Authenticity, identity, genomic stability and status of differentiation. Transfus Med Hemother 37: 57-64 (2010).

340. Röhrs S, Scherr M, Romani J, Zaborski M, Drexler HG, Quentmeier H: CD7 in acute myeloid leukemia: Correlation with loss of wild-type CEBPA, consequence of epigenetic regulation. J Hematol Oncol 3: 15 (2010). PubMedID 20398252

339. Ivanyi P, Morgan M, Piao W, Ukena SN, Steube K, Ganser A, Franzke A: Pre T-cell receptor alpha (pTalpha) expression patterns and functional analysis in human T-cell lymphoblastic leukemia. Cellular Oncology 32: 101-108 (2010). PubMedID 20208138

338. Carbone A, Cesarman E, Gloghini A, Drexler HG: Understanding pathogenetic aspects and clinical presentation of primary effusion lymphoma through its derived cell lines. AIDS 24: 479-490 (2010). PubMedID 20051807

337. Nagel S, Venturini L, Meyer C, Kaufmann M, Scherr M, Drexler HG, MacLeod RAF: Multiple mechanisms induce ectopic expression of LYL1 in subsets of T-ALL cell lines. Leukemia Res 34: 521-528 (2010). PubMedID 19608273

336. May T, Butueva M, Bantner S, Markusic D, Seppen J, MacLeod RAF, Weich H, Hauser H, Wirth D: Synthetic gene regulation circuits for control of cell expansion. Tissue Engineering Part A: 16: 441-452 (2010). PubMedID 19705962

335. Dirks WG, MacLeod RAF, Nakamura Y, Kohara A, Reid Y, Milch H, Drexler HG, Mizusawa H: Cell line cross-contamination initiative: An interactive reference database of STR profiles covering common cancer cell lines. Int J Cancer 126: 302-304 (2010). PubMedID 19859913

334. Röhrs S, Dirks WG, Meyer C, Marschallek R, Scherr M, Slany R, Wallace A, Drexler HG, Quemtmeier H: Hypomethylation and expression of BEX2, IGSF4 and TIMP3 indicative of MLL translocations in acute myeloid leukemia. Mol Cancer 8: 86 (2009). PubMedID 19835597

333. Nagel S, Venturini L, Przybylski GK, Grabarczyk P, Meyer C, Kaufmann M, Battmer K, Schmidt CA, Drexler HG, Scherr M, MacLeod RAF: NK-like homeodomain proteins activate NOTCH3-signaling in leukemic T-cells. BMC Cancer 9: 371 (2009). PubMedID 19835636

332. Chen S, MacLeod RAF, Dirks WG, Drexler HG, Xue YQ: False leukemia and lymphoma cell lines. Int J Blood Transfusion Hematology 32: 342-346 (2009).

331. Drexler HG, MacLeod RAF: Malignant hematopoietic cell lines: In vitro models for the study of plasmacytoid dendritic cell leukemia. Leukemia Res 33: 1166-1176 (2009). PubMedID 19423163

330. Röhrs S, Romani J, Zaborski M, Drexler HG, Quentmeier H: Hypermethylation of Death-Associated Protein Kinase 1 (DAPK1) differentiates natural killer cell lines from cell lines derived from T-acute lymphoblastic leukemia. Leukemia 23: 1174-1176 (2009). PubMedID 19212339

329. Drexler HG, Dirks WG, MacLeod RAF: Many are called MDS cell lines: One is chosen. Leukemia Res 33: 1011-1016 (2009). PubMedID 19344951

328. Suzuki S, Nagel S, Schneider B, Chen S, Kaufmann M, Uozumi K, Arima N, Drexler HG, MacLeod RAF: A second NOTCH1 chromosome rearrangement: t(9;14)(q34.3;q11). Leukemia 23: 1003-1006 (2009). PubMedID 19151773

327. Reindl C, Quentmeier H, Petropoulos K, Greif PA, Benthaus T, Argiropoulos B, Mellert G, Vempati S, Duyster J, Buske C, Bohlander SK, Humphries KR, Hiddemann W, Spiekermann K: CBL exon 8/9 mutants activate the FLT3 pathway and cluster in core binding factor/11q deletion acute myeloid leukemia/myelodysplastic syndrome subtypes. Clin Cancer Res 15: 2238-2247 (2009). PubMedID 19276253

326. Martín-Subero JI, Kreuz M, Bibikova M, Bentink S, Ammerpohl O, Wickham-Garcia E, Rosolowski M, Richter J, Lopez-Serra L, Ballestar E, Berger H, Agirre X, Bernd HW, Calvanese V, Cogliatti SB, Drexler HG, Fan JB, Fraga MF, Hansmann ML, Hummel M, Klapper W, Korn B, Küppers R, MacLeod RAF, Möller P, Ott G, Pott C, Prosper F, Rosenwald A, Schwaenen C, Schübeler D, Seifert M, Stürzenhofecker B, Weber M, Wessendorf S, Loeffler M, Trümper L, Stein H, Spang R, Esteller M, Barker D, Hasenclever D, Siebert R: New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling. Blood 113: 2488-2497 (2009). PubMedID 19075189

325. Greulich-Bode KM, Kaufmann M, Gilbertz K, MacLeod RAF: Tips and tricks for mFISH. in: Fluorescence in Situ Hybridization (FISH) - Application Guide (ed Liehr T), Springer, Berlin, Heidelberg, Germany (2009), pp. 183-192.

324. Quentmeier H, Schneider B, Röhrs S, Romani J, Zaborski M, MacLeod RAF, Drexler HG: SET-NUP214 fusion in acute myeloid leukemia- and T-cell acute lymphoblastic leukemia-derived cell lines. J Hematol Oncol 2: 3 (2009). PubMedID 19166587

323. Markoullis K, Bulian D, Hölzlwimmer G, Quintanilla-Martinez L, Heiliger K-J, Zitzelsberger H, Scherb H, Mysliwietz J, Uphoff CC, Drexler HG, Adler T, Busch DH, Schmidt J, Mahabir E: Mycoplasma contamination of murine embryonic stem cells affects cell parameters, germ line transmission and chimeric progeny. Transgenic Res 18: 71-87 (2008). PubMedID 18819014

322. Nagel S, Venturini L, Przybylski GK, Grabarczyk P, Schmidt CA, Meyer C, Drexler HG, MacLeod RAF, Scherr M: Activation of miR-17-92 by NK-like homeodomain proteins suppresses apoptosis via reduction of E2F1 in T-ALL. Leukemia Lymphoma 50: 101-108 (2009). PubMedID 19148830

321. Schneider B, Nagel S, MacLeod RAF: t(3;7)(q27;q32). Atlas of Genetics and Cytogenetics in Oncology and Haematology. December 2008.
URL: http://atlasgeneticsoncology.org/Anomalies/t0307q27q32ID1515.html

320. Quentmeier H, Geffers R, Jost E, MacLeod RAF, Nagel S, Röhrs S, Romani J, Scherr M, Zaborski M, Drexler HG: SOCS2: Inhibitor of JAKV617F-mediated signal transduction. Leukemia 22: 2169-2175 (2008). PubMedID 18769447

319. Virappane P, Gale R, Hills R, Kakkas I, Summers K, Stevens J, Allen C, Green C, Quentmeier H, Drexler HG, Burnett A, Linch D, Bonnet D, Lister TA, Fitzgibbon J: Mutation of the Wilms´ tumor 1 gene is a poor prognostic factor associated with chemo-resistance in normal karyotype acute myeloid leukemia: the United Kingdom Medical Research Council Adult Leukaemia Working Party. J Clin Oncol 26: 5429-5435 (2008). PubMedID 18591546

318. Nagel S, MacLeod RAF, Drexler HG: The role of E2F factors in lymphoma. in: Control of Cellular Physiology by Transcription Factors E2F (ed Yoshida K), Research Signpost, Kerala, India (2008), pp. 243-256.

317. Drexler HG, MacLeod RAF: Malignant hematopoietic cell lines: In vitro models for the study of Waldenström´s macroglobulinemia. Leukemia Res 32: 1669-1673 (2008). PubMedID 18533260

316. Nagel S, MacLeod RAF: t(5;14)(q35;q32.2). Atlas of Genetics and Cytogenetics in Oncology and Haematology. May 2008.
URL: http://atlasgeneticsoncology.org/Anomalies/t0514q35q32ID1386.html

315. MacLeod RAF, Drexler HG: Cell lines are robust in vitro models. Brit J Haematol 142: 137-138 (2008). PubMedID 18445085

314. Chen S, MacLeod RAF, Drexler HG, Xue Y: Human HUVEC ECV304 is actually human bladder cell line T-24. Chinese J Medicine 88: 1296 (2008).

313. Schneider B, Nagel S, Kaufmann M, Winkelmann S, Bode J, Drexler HG, MacLeod RAF: t(3;7)(q27;q32) fuses BCL6 to a non-coding region at FRA7H near miR-29. Leukemia 22: 1262-1266 (2008). PubMedID 17989715

312. Nagel S, Meyer C, Quentmeier H, Kaufmann M, Drexler HG, MacLeod RAF: MEF2C is activated by multiple mechanisms in a subset of T-acute lymphoblastic leukemia cell lines. Leukemia 22: 600-607 (2008). PubMedID 18079734

311. MacLeod RAF, Dirks WG, Drexler HG: One falsehood leads easily to another. Int J Cancer 122: 2165-2168 (2008). PubMedID 18172862

310. Nagel S, Leich E, Quentmeier H, Meyer C, Kaufmann M, Drexler HG, Zettl A, Rosenwald A, MacLeod RAF: Amplification at 7q22 targets cyclin-dependent kinase 6 in T-cell lymphoma. Leukemia 22: 387-392 (2008). PubMedID 17989712

309. MacLeod RAF, Nagel S, Scherr M, Schneider B, Dirks WG, Uphoff CC, Quentmeier H, Drexler HG: Human leukemia and lymphoma cell lines as models and resources. Current Medicinal Chemistry 15: 339-359 (2008). PubMedID 18288989

308. Steube KG, Koelz AL, Drexler HG: Identification and verification of rodent cell lines by polymerase chain reaction. Cytotechnology 56: 49-56 (2008).

307. Staber PB, Vesely P, Hag N, Ott RG, Funato K, Bambach I, Fuchs C, Schauer S, Linkesch W, Hrzenjak A, Dirks WG, Sexl V, Bergler H, Kadin ME, Sternberg DW, Kenner L, Hoefler G: The oncoprotein NPM-ALK of anaplastic large-cell lymphoma induces JUNB transcription via ERK1/2 and JunB translation via mTOR signaling. Blood 110: 3374-3383 (2007). PubMedID 17690253

306. El Fitori J, Su Y, Buchler P, Ludwig R, Giese NA, Buchler MW, Quentmeier H, Hines OJ, Herr I, Friess H: PKC 412 small-molecule tyrosine kinase inhibitor: single-compound therapy for pancreatic cancer. Cancer 110: 1457-1468 (2007). PubMedID 17676584

305. Nagel S, MacLeod RAF: IL6 (Interleukin 6). Atlas of Genetics and Cytogenetics in Oncology and Haematology. April 2007.
URL: http://atlasgeneticsoncology.org/Genes/IL6ID519ch7p15.html

304. Nagel S, Burek C, Venturini L, Scherr M, Quentmeier H, Meyer C, Rosenwald A, Drexler HG, MacLeod RAF: Comprehensive analysis of homeobox gene expression in Hodgkin lymphoma cell lines identifies dysregulated expression of HOXB9 mediated via ERK5 signalling and BMI1. Blood 109: 3015-3023 (2007). PubMedID 17148583

303. MacLeod RAF, Kaufmann M, Drexler HG: Cytogenetic harvesting of commonly used tumor cell lines. Nature Protocols 2: 372-382 (2007). PubMedID 17406598

302. Sandberg Y, Verhaaf B, van Gastel-Mol EJ, Wolvers-Tettero IL, de Vos J, MacLeod RAF, Noordzij JG, Dik WA, van Dongen JJ, Langerak AW: Human T-cell lines with well defined T-cell receptor gene rearrangements as controls for the BIOMED-2 multiplex polymerase chain reaction tubes. Leukemia 21: 230-237 (2007). PubMedID 17170727

300. MacLeod RAF, Drexler HG: Conservation of unreposited cell lines. Cytogenet Genome Res 116: 152 (2007). PubMedID 17268196

299. Nagel S, Scherr M, Kel A, Hornischer K, Crawford GE, Kaufmann M, Meyer C, Drexler HG, MacLeod RAF: Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-cell acute lymphoblastic leukemia by remote 3´-BCL11B enhancers and coregulation by PU.1 and HMGA1. Cancer Res: 1461-1471 (2007). PubMedID 00000000


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298. Burmeister T, MacLeod RAF, Reinhardt R, Mansmann V, Loddenkemper C, Marinets O, Drexler HG, Thiel E, Blau IW: A novel sporadic Burkitt lymphoma cell line (BLUE-1) with a unique t(6;10)(q15;q11.2) rearrangement. Leukemia Res 30: 1417-1423 (2006). PubMedID 16697040

297. Burnett TA, Dinkla K, Rohde M, Chhatwal GS, Uphoff C, Srivastava M, Cordwell SJ, Geary S, Liao X, Minion FC, Walker MJ, Djordjevic SP: P159 is a proteolytically processed, surface adhesin of Mycoplasma hyopneumoniae: defined domains of P159 bind heparin and promote adherence to eukaryote cells. Mol Microbiol 60: 669-686 (2006). PubMed ID 16629669

296. Drexler HG, MacLeod RAF: Mantle cell lymphoma-derived cell lines: Unique research tools. Leukemia Res 30: 911-913 (2006). PubMedID 16563503

295. Quentmeier H, MacLeod RAF, Zaborski M, Drexler HG: JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders. Leukemia 20: 471-476 (2006). PubMed ID 16408098

294. MacLeod RAF, Drexler HG: Public repositories: Users reluctant to give materials. Nature 439: 912 (2006).

293. Drexler HG: New mantle cell lymphoma-derived cell line: MAVER-1. Haematologica 91: 2 (2006).

292. MacLeod RAF, Nagel S: E2F3 (E2F transcription factor 3). Atlas of Genetics and Cytogenetics in Oncology and Haematology. July 2005.
URL: http://www.infobiogen.fr/services/chromcancer/Genes/E2F3ID40384ch6p22.html

291. Drexler HG: Guide to Leukemia-Lymphoma Cell Lines. Braunschweig, 2005, eBook CD.

290. Quentmeier H, Martelli MP, Dirks WG, Bolli N, Liso A, MacLeod RAF, Nicoletti I, Manucci R, Pucciarini A, Bigerna B, Martelli MF, Mecucci C, Drexler HG, Falini B: The cell line OCI/AML3 bears exon-12 NPM gene mutation-A and cytoplasmic expression of nucleophosmin. Leukemia 19: 1760-1767 (2005). PubMed ID 16079892

289. Quentmeier H, Tonelli R, Geffers R, Pession A, Uphoff CC, Drexler HG: Expression of BEX1 in acute myeloid leukemia with MLL rearrangements. Leukemia 19: 1488-1489 (2005). PubMed ID 15920485

288. Drexler HG, Quentmeier H, MacLeod RAF: Cell line models of leukemia. Drug Discovery Today - Disease Models 2: 51-56 (2005).

287. Harashima A, Matsuo Y, Drexler HG, Okochi A, Motoda R, Tanimoto M, Orita K: Transcription factor expression in B-cell precursor-leukemia cell lines: Preferential expression of T-bet. Leukemia Res 29: 841-848 (2005). PubMed ID 15927679

286. Dirks WG, Fähnrich S, Estella IAJ, Drexler HG: Short tandem repeat DNA typing provides an international reference standard for authentication of human cell lines. ALTEX 22: 3-9 (2005). PubMed ID 15953965

285. Matsuo Y, Drexler HG, Harashima A, Okochi A, Kojima K, Asakura S, Tanimoto M, Orita K: Acute myeloid leukemia cell lines MOLM-17 and MOLM-18 derived from patient with advanced myelodysplastic syndromes. Leukemia Res 29: 701-710 (2005). PubMed ID 15863212

284. Nagel S, Scherr M, Quentmeier H, Kaufmann M, Zaborski M, Drexler HG, MacLeod RAF: HLXB9 activates IL6 in Hodgkin lymphoma cell lines and is regulated by PI3K signalling involving E2F3. Leukemia 19: 841-846 (2005). PubMed ID 15772702

283. MacLeod RAF, Nagel S: NKX2-5 (NK2 transcription factor related locus 5 (Drosophila). Atlas of Genetics and Cytogenetics in Oncology and Haematology. March 2005.
URL: http://www.infobiogen.fr/services/chromcancer/Genes/NKX25ID42958ch5q35.html

282. Quentmeier H, Cools J, MacLeod RAF, Marynen P, Uphoff CC, Drexler HG: e6-a2 BCR/ABL fusion in T-acute lymphoblastic leukemia. Leukemia 19: 295-296 (2005). PubMed ID 15565165

281. Nagel S, Kaufmann M, Scherr M, Drexler HG, MacLeod RAF: Activation of HLXB9 by juxtaposition with MYB via formation of t(6;7)(q23;q36) in an AML-M4 cell line (GDM-1). Genes Chromosomes Cancer 42: 170-178 (2005). PubMed ID 15540222

280. MacLeod RAF, Drexler HG: Cytogenetic Analysis of Cell Lines. in: Basic Cell Culture Protocols, Third Edition (eds Helgason CD, Miller CL), Humana Press, Totowa, NJ (2005), pp. 51-70. PubMed ID 15361655

279. Dirks WG, Drexler HG: Authentication of Scientific Human Cell Lines: Easy-to-Use DNA Fingerprinting. in: Basic Cell Culture Protocols, Third Edition (eds Helgason CD, Miller CL), Humana Press, Totowa, NJ (2005), pp. 35-50. PubMed ID 15361654

278. Uphoff CC, Drexler HG: Eradication of Mycoplasma Contaminations. in: Basic Cell Culture Protocols, Third Edition (eds Helgason CD, Miller CL), Humana Press, Totowa, NJ (2005), pp. 25-34. PubMed ID 15361653

277. Uphoff CC, Drexler HG: Detection of Mycoplasma Contaminations. in: Basic Cell Culture Protocols, Third Edition (eds Helgason CD, Miller CL), Humana Press, Totowa, NJ (2005), pp. 13-24. PubMed ID 15361652

276. Stackebrandt E, Brambilla E, Cousin S, Dirks W, Pukall R: Culture-independent analysis of bacterial species from an anaerobic mat from Lake Fryxell, Antarctica: prokaryotic diversity revisited. Cell Mol Biol 50: 517-524 (2004). PubMed ID 15559968

275. MacLeod RAF, Nagel S: BCL11B (B cell lymphoma/leukaemia 11B). Atlas of Genetics and Cytogenetics in Oncology and Haematology. July 2004.
URL: http://www.infobiogen.fr/services/chromcancer/Genes/BCL11BID392.html

274. Hiort J, Maksimenka K, Reichert M, Perovic-Ottstadt S, Lin WH, Wray V, Steube K, Schaumann K, Weber H, Proksch P, Ebel R, Muller WE, Bringmann G: New natural products from the sponge-derived fungus Aspergillus niger. J Nat Prod 67: 1532-1543 (2004). PubMed ID 15387655

273. Drexler HG, Matsuo Y, MacLeod RAF: Malignant hematopoietic cell lines: In vitro models for the study of erythroleukemia. Leukemia Res 28: 1243-1251 (2004). PubMed ID 15475063

272. Drexler HG, MacLeod RAF: Malignant hematopoietic cell lines: In vitro models for the study of anaplastic large-cell lymphoma. Leukemia 18: 1569-1571 (2004). PubMed ID 15356658

271. Graux C, Cools J, Melotte C, Quentmeier H, Ferrando A, Levine R, Vermeesch J, Stul M, Dutta B, Boeckx N, Bosly A, Heimann P, Uyttebroeck A, Mentens N, Somers R, MacLeod RAF, Drexler HG, Look TA, Gilliland DG, Michaux L, Vandenberghe P, Wlodarska I, Marynen P, Hagemeijer A: Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia. Nature Genetics 36: 1084-1089 (2004). PubMed ID 15361874

270. Matsuo Y, Drexler HG, Harashima A, Okochi A, Shimizu N, Orita K: Transcription factor expression in cell lines derived from natural killer-cell and natural killer-like T-cell leukemia-lymphoma. Human Cell 17: 85-92 (2004). PubMed ID 15369140

269. Rudolph C, Steinemann D, von Neuhoff N, Gadzicki D, Ripperger T, Drexler HG, Mrasek K, Liehr T, Claussen U, Emura M, Schrock E, Schlegelberger B: Molecular characterization of the mantle cell lymphoma cell line GRANTA-519. Cancer Genet Cytogenet 153: 144-150 (2004). PubMed ID 15350304

268. MacLeod RA, Nagel S, Drexler HG: BCL11B rearrangements probably target T-cell neoplasia rather than acute myelocytic leukemia. Cancer Genetics Cytogenetics 153: 88-89 (2004). PubMed ID 15325104

267. Van Zutven LJCM, Velthuizen SCJM, Wolvers-Tettero ILM, Van Dongen JJM, Poulsen TS, MacLeod RAF, Beverloo HB, Langerak AW: Two dual-color split signal fluorescence in situ hybridzation assays to detect t(5;14) involving HOX11L2 or CSX in T-cell acute lymphoblastic leukemia. Haematologica 89: 671-678 (2004). PubMed ID 15194534

266. Steube KG, Meyer C, Uphoff CC, Drexler HG: A simple method using ß-globin polymerase chain reaction for the species identification of animal cell lines - A progress report. In Vitro Cell Dev Biol 39: 468-475 (2003). PubMed ID 14640788

265. Matsuo Y, Drexler HG, Harashima A, Okochi A, Kojima K, Orita K: Induction of CD28 on the new myeloma cell line MOLP-8 with t(11;14)(q13;q32) expressing delta/lambda type immunoglobulin.
Leukemia Res 28: 869-877 (2004). PubMed ID 15203285

264. Drexler HG, Quentmeier H: FLT3: Receptor and ligand. Growth Factors 22: 71-73 (2004).PubMed ID 15253381

263. MacLeod RAF, Nagel S: TLX3 (T-cell leukemia, homeobox protein 3). Atlas Genet Cytogenet Oncol Haematol. March 2004.
URL: http://www.infobiogen.fr/services/chromcancer/Genes/TLX3ID398.html

262. Hu ZB, Quentmeier H, Meyer C, Kaufmann M, MacLeod RAF, Drexler HG: New cytokine-dependent acute myeloid leukemia cell line MUTZ-11 with disomic chromosome rearrangement t(16;17). Leukemia Res 28: 509-515 (2004). PubMed ID 15068904

261. Cools J, Quentmeier H, Huntly BJP, Marynen P, Griffin JD, Drexler HG, Gilliland DG: The EOL-1 cell line as an in vitro model for the study of FIP1L1-PDGFRA-positive chronic eosinophilic leukemia. Blood 103: 2802-2805 (2004). PubMed ID 14630792

260. Drexler HG, Quentmeier H, MacLeod RAF: Malignant hematopoietic cell lines: In vitro models for the study of MLL gene alterations. Leukemia 18: 227-232 (2004). PubMed ID 14671638

259. Jadulco R, Edrada RE, Ebel R, Berg A, Schaumann K, Wray V, Steube K, Proksch P: New communesin derivatives from the fungi Penicillium spp. derived from the mediterranean marine sponge Axinella verrucosa. J Nat Prod 67: 78-81 (2004). PubMed ID 14738391

258. Matsuo Y, Drexler HG, Harashima A, Takenaka K, Ishihara T, Ishimaru F, Orita K: A novel ALL-L3 cell line, BALM-25, expressing both immunoglobulin light chains. Leukemia Lymphoma 45: 575-581 (2004).

257. Quentmeier H, Dirks WG, MacLeod RAF, Reinhardt J, Zaborksi M, Drexler HG: Expression of HOX genes in acute leukemia cell lines with and without MLL translocations. Leukemia Lymphoma 45: 567-574 (2004).

256. Uphoff CC, Drexler HG: Elimination of Mycoplasma from Infected Cell Lines Using Antibiotics. in: Cancer Cell Culture - Methods and Protocols (ed Langdon SP, Humana Press, Totowa, NJ (2004), pp. 327-334. PubMed ID 14634245

255. Uphoff CC, Drexler HG: Detecting Mycoplasma Contamination in Cell Cultures by Polymerase Chain Reaction (PCR). in: Cancer Cell Culture - Methods and Protocols (ed Langdon SP), Humana Press, Totowa, NJ (2004), pp. 319-326. PubMed ID 14634244

254. Drexler HG: Isolation and Culture of Leukemia Cell Lines. in: Cancer Cell Culture - Methods and Protocols (ed Langdon SP), Humana Press, Totowa, NJ (2004), pp PubMed ID 14634225

253. MacLeod RAF, Drexler HG: Cytogenetic characterization of Tumor Cell Lines. in: Cancer Cell Culture - Methods and Protocols (ed Langdon SP), Humana Press, Totowa, NJ (2004), pp. 57-76. PubMed ID 14634218

252. Dirks WG, Drexler HG: Authentication of Cancer Cell Lines by DNA Fingerprinting. in: Cancer Cell Culture - Methods and Protocols (ed Langdon SP, Humana Press, Totowa, NJ (2004), pp. 43-55. PubMed ID 14634217

251. Drexler HG, Matsuo Y, MacLeod RAF: Persistent use of false myeloma cell lines. Human Cell 16: 101-105 (2003).

250. Drexler HG: Establishment and Culture of Human Leukemia-Lymphoma Cell Lines. in: Culture of Tumor Cells - Culture of Specialized Cells (eds Pfragner R, Freshney RI), Wiley, New York (2003), pp. 319-348.

249. Erck C, MacLeod RAF, Wehland J: Cloning and genomic organization of the TTL gene on mouse chromosome 2 and human chromosome 2q13. Cytogenet Genome Res 101: 47-53 (2003). PubMed ID 14571137

248. Drexler HG, MacLeod RAF: Leukemia-lymphoma cell lines as model systems for hematopoietic research. Annals Medicine 35: 404-412 (2003). PubMed ID 14572164

247. Nagel S, Kaufmann M, Drexler HG, MacLeod RAF: The cardiac homeobox gene NKX2-5 is deregulated by juxtaposition with BCL11B in pediatric T-ALL cell lines via a novel t(5;14)(q35.1;q32.2).
Cancer Res 63: 5329-5334 (2003). PubMed ID 14500364

246. Proksch P, Ebel R, Edrada RA, Schupp P, Lin WH, Sudarsono, Wray W, Steube K: Detection of pharmacologically active natural products using ecology. Selected examples from Indopacific marine invertebrates and sponge-derived fungi. Pure Appl Chem 75: 343-352 (2003).

245. Efferth T, Sauerbrey A, Steinbach D, Gebhart E, Drexler HG, Miyachi H, Chitambar R, Becker CM, Zintl F, Humeny A: Analysis of single nucleotide polymorphism 3435T of the multidrug resistance gene MDR1 in acute lymphoblastic leukemia. Int J Oncol 23: 509-517 (2003). PubMed ID 12851703

244. Steube KG, Meyer C, Schupp P, Proksch P, Drexler HG: Differential effects of staurosporine and its analogues on chemokine release in promyelocytic leukemia cell line NB-4. Leukemia Res 27: 957-963 (2003). PubMed ID 12860017

243. Matsuo Y, Drexler HG: Immunoprofiling of cell lines derived from natural killer-cell and natural killer-like T-cell leukemia-lymphoma. Leukemia Res 27: 935-945 (2003). PubMed ID 12860014

242. Drexler HG, MacLeod RAF: Malignant hematopoietic cell lines: In vitro models for the study of mast cell leukemia. Leukemia Res 27: 671-676 (2003). PubMed ID 12801523

241. MacLeod RAF, Dirks W, Drexler HG: Characterizing stem cell lines. Science 3000: 911-912 (2003).

240. Fleckenstein DS, Dirks WG, Drexler HG, Quentmeier H: Tumor necrosis factor receptor-associated factor (TRAF) 4 is a new ligand of the p70S6 serine/threonine kinase. Leukemia Res 27: 687-694 (2003). PubMed ID 12801526

239. Quentmeier H, Reinhardt J, Zaborski M, Drexler HG: MLL partial tandem duplications in acute leukemia cell lines. Leukemia 17: 980-981 (2003). PubMed ID 12750714

238. Wang CY, Wang BG, Wiryowidagdo S, Wray V, van Soesr R, Steube KG, Guan HS, Proksch P, Ebel R: Melophlins C-0, thirteen novel tetramic acids from the marine sponge Melophlus sarassinorum.J Nat Prod 66: 51-56 (2003). PubMed ID 12542345

237. Quentmeier H, Reinhardt J, Zaborski M, Drexler HG: Granulocyte-macrophage colony-stimulating factor: Inhibitor of tumor necrosis factor-induced apoptosis. Leukemia Res 27: 539-545 (2003). PubMed ID 12648514

236. MacLeod RAF, Nagel S, Kaufmann M, Janssen JWG, Drexler HG: Activation of HOX11L2 by juxtaposition with 3'-BCL11B in an acute lymphoblastic leukemia cell line (HPB-ALL) with t(5;14)(q35;q32.2). Genes Chromosomes Cancer 37: 84-91 (2003). PubMed ID 12661009

235. Quentmeier H, Fleckenstein D, Dirks WG, Uphoff CC, Zaborski M, Drexler HG: GM-CSF is the mediator of the proliferative effect of tumor necrosis factor alpha in acute myelid leukemia-derived cell lines. in: Acute Leukemias IX (eds Hiddemann W et al), Springer, Berlin (2003), pp. 267-272.

234. Hu ZB, Quentmeier H, Meyer C, MacLeod RAF, Drexler HG: Establishment of the two cytokine-dependent acute myeloid leukemia-derived leukemia cell lines MUTZ-8 and MUTZ-11. in: Acute Leukemias IX (eds Hiddemann W et al), Springer, Berlin (2003), pp. 122-127.

233. Meyer C, MacLeod RAF, Quentmeier H, Janssen JWG, Coignet L, Drexler HG: Establishment of the B-cell precursor-acute lymphoblastic leukemia cell line MUTZ-5 carrying a (12;13) translocation. in: Acute Leukemias IX (eds Hiddemann W et al), Springer, Berlin (2003), pp. 15-18.

232. Drexler HG, Dirks WG, Matsuo Y, MacLeod RAF: False leukemia-lymphoma cell lines: An update on over 500 cell lines. Leukemia 17: 416-426 (2003). PubMed ID 12592342

231. Matsuo Y, Drexler HG, Kaneda K, Kojima K, Ohtsuki Y, Hara M, Yasukawa M, Tanimoto M, Orita K: Megakaryoblastic leukemia cell line MOLM-16 derived from minimally differentiated acute leukemia with myeloid/NK precursor phenotype. Leukemia Res 27: 165-171 (2003). PubMed ID 12526922

230. Quentmeier H, Reinhardt J, Zaborski M, Drexler HG: FLT3 mutations in acute myeloid leukemia cell lines.Leukemia 17: 120-124 (2003). PubMed ID 12529668

229. Drexler HG, Uphoff CC: Mycoplasma contamination of cell cultures: Incidence, sources, effects, detection, elimination, prevention. Cytotechnology 39: 23-38 (2002).

228. Matsuo Y, Drexler HG, Harashima A, Fujii N, Ishimaru F, Orita K: Establishment and characterization of new B-cell precursor leukemia cell line NALM-35. Human Cell 15: 215-223 (2002). PubMed ID 12889857

227. Matsuo Y, Drexler HG, Sugimoto A, Harashima A, Okochi A, Kojima K, Orita K: Novel B-cell acute lymphoblastic leukemia sister cell lines BALM 19-23 and BALM-26 with interclonal proliferative and phenotypic heterogeneity derived from a patient with hypercalcemia. Human Cell 15: 160-170 (2002). PubMed ID 12703546

226. Edrada RA, Ebel R, Supriyono A, Wray V, Schupp P, Steube K, van Soest R, Proksch P: Swinhoeiamide A, a new highly active calyculin derivative from the marine sponge Theonella swinhoei. J Nat Prod 65: 1168-1172 (2002). PubMed ID 12193024

225. Efferth T, Verdorfer I, Miyachi H, Sauerbrey A, Drexler HG, Chitambar CR, Haber M, Gebhart E: Genomic imbalances in drug-resistant T-cell acute lymphoblastic CEM leukemia cell lines. Blood Cells Mol Dis 29: 1-13 (2002). PubMed ID 12482398

224. MacLeod RAF, Nagel S, Kaufmann M, Greulich-Bode K, Drexler HG: Multicolor-FISH analysis of a natural killer cell line (NK-92).Leukemia Res 26: 1027-1033 (2002). PubMed ID 12363472

223. Gebhart E, Thoma K, Verdorfer I, Drexler HG, Efferth T: Genomic imbalances in T-cell acute lymphoblastic leukaemia cell lines. Int J Oncol 21: 887-894 (2002). PubMed ID 12239631

222. Drexler HG, Quentmeier H, Dirks WG, MacLeod RAF: Bladder carcinoma cell line ECV304 is not a model system for endothelial cells. In Vitro Cell Dev Biol Anim 38: 185-186 (2002). PubMed ID 12197766

221. Drexler HG, Quentmeier H, Dirks WG, Uphoff CC, MacLeod RAF: DNA profiling and cytogenetic analysis of cell line WSU-CLL reveal cross-contamination with cell line REH (pre B-ALL). Leukemia 16: 1868-1870 (2002). PubMed ID 12200708

220. Hu ZB, MacLeod RAF, Meyer C, Quentmeier H, Drexler HG: New acute myeloid leukemia-derived leukemia cell line: MUTZ-8 with 5q-.Leukemia 16: 1556-1561 (2002). PubMed ID 12145698

219. Matsuo Y, Drexler HG, Takeuchi M, Tanaka M, Orita K: Establishment of the T-cell large granular lymphocyte leukemia cell line MOTN-1 carrying natural killer-cell antigens. Leukemia Res 26: 873-879 (2002). PubMed ID 12127564

218. Drexler HG, MacLeod RAF: Malignant hematopoietic cell lines: In vitro models for the study of mantle cell lymphoma. Leukemia Res 26: 781-787 (2002). PubMed ID 12127550

217. Matsuo Y, Drexler HG, Takeuchi M, Orita K: A novel L3-acute lymphoblastic leukemia cell line (BALM-27) carrying cytoplasmic Ig chain but lacking expression of cell surface Ig chains. Leukemia Lymphoma 43: 1441-1446 (2002). PubMed ID 12389627

216. Dirks WG, Fähnrich S, Lis Y, Becker E, MacLeod RAF, Drexler HG: Expression and functional analysis of the anaplastic lymphoma kinase (ALK) gene in tumor cell lines. Int J Cancer 100: 49-56 (2002). PubMed ID 12115586

215. Efferth T, Miyachi H, Drexler HG, Gebhart E: Methylthioadenosine phosphorylase as target for chemoselective treatment of T-cell acute lymphoblastic leukemic cells. Blood Cells Mol Dis 28: 47-56 (2002). PubMed ID 11987241

214. Matsuo Y, Drexler HG, Okochi A, Sugimoto A, Harashima A, Orita K: Expression and distribution of NK-associated antigens: Investigations using leukaemia/lymphoma-derived cell lines.in: Leucocyte Typing VII (eds Mason D et al), Oxford University Press, Oxford (2002), pp. 431-434.

213. Quentmeier H, Drexler HG:The DSMZ: Cell bank for immortalized cell lines and hybridomas.in: Leucocyte Typing VII (eds Mason D et al), Oxford University Press, Oxford (2002), pp. 403-404.

212. Matsuo Y, Drexler HG, Okochi A, Sugimoto A, Harashima A, Orita K:Characterization of human B-cell-precursor leukaemia and mature B-cell-leukaemia/lymphoma cell lines: Expression and distribution of human pre-B-cell receptor.in: Leucocyte Typing VII (eds Mason D et al), Oxford University Press, Oxford (2002), pp. 117-120.

211. Uphoff CC, Drexler HG:Comparative antibiotic eradication of mycoplasma infections from continuous cell lines.In Vitro Cell Dev Biol Anim 38: 86-89 (2002). PubMed ID 11929000

210. Uphoff CC, Drexler HG:Comparative PCR analysis for detection of mycoplasma infections in continuous cell lines.In Vitro Cell Dev Biol Anim 38: 79-85 (2002). PubMed ID 11928999

209. Lamp EC, Drexler HG:Tartrate-Resistant Acid Phosphatase.in: The Encyclopedia of Molecular Medicine (ed Creighton TE), Wiley, New York. (2002), pp. 3094-3097.

208. Uphoff CC, Drexler HG:Monocyte Specific Carboxylesterase. in: The Encyclopedia of Molecular Medicine (ed Creighton TE), Wiley, New York. (2002), pp. 2128-2132.

207. Drexler HG: INK4 Proteins.in: The Encyclopedia of Molecular Medicine (ed Creighton TE), Wiley, New York (2002), pp. 1751-1755.

206. Uphoff CC, Drexler HG: Detection of mycoplasma in leukemia-lymphoma cell lines using polymerase chain reaction. Leukemia 16: 289-293 (2002). PubMed ID 11840297

205. Uphoff CC, Meyer C, Drexler HG: Elimination of mycoplasma from leukemia-lymphoma cell lines using antibiotics.Leukemia 16: 284-288 (2002). PubMed ID 11840296

204. Drexler HG, Uphoff CC, Dirks WG, MacLeod RAF: Mix-ups and mycoplasma: The enemies within. Leukemia Res 26: 329-333 (2002). PubMed ID 11839374

203. Drexler HG, Matsuo Y: What is an "NK-precursor cell line"? Leukemia Res 26: 297-299 (2002). PubMed ID 11792419

202. MacLeod RAF, Dirks WG, Drexler HG: Persistent use of misidentified cell lines and its prevention. Genes Chromosomes Cancer 33: 103-105 (2002). PubMed ID 11746993

201. Fleckenstein DS, Uphoff CC, Drexler HG, Quentmeier H: Detection of p53 gene mutations by single strand conformational polymorphism (SSCP) in human acute myeloid leukemic-derived cell lines. Leukemia Res 26: 207-214 (2002). PubMed ID 11755471

200. Matsuo Y, Drexler HG, Takeuchi M, Orita K: Establishment of novel B-cell precursor leukemia sister cell lines NALM-36 and NALM-37: Shift of immunoglobulin phenotype to double light chain positive B-cell. Leukemia Res 26: 1-10 (2002). PubMed ID 11734297

199. Wang BG, Ebel R, Nugroho BW, Prijono D, Frank W, Steube KG, Hao XJ, Proksch P: Aglacins A-D, first representatives of a new class of aryltetralin cyclic ether lignans Aglaia cordata. J Nat Prod 64: 1521-1526 (2001). PubMed ID 11754603

198. Schupp P, Steube K, Meyer C, Proksch P: Anti-proliferative effects of new staurosporine derivatives isolated from a marine ascidian and its predatory flatworm.
Cancer Letters 174: 165-172 (2001). PubMed ID 11689292

197. Uphoff CC, Drexler HG: Prevention of mycoplasma contamination in leukemia-lymphoma cell lines.Human Cell 14: 244-247 (2001). PubMed ID 11774744

196. Drexler HG, MacLeod RAF, Dirks WG: Cross-contamination: HS-Sultan is not a myeloma but a Burkitt lymphoma cell line.Blood 98: 3495-3496 (2001). PubMed ID 11732505

195. Quentmeier H, Osborn M, Reinhardt J, Zaborski M, Drexler HG: Immunocytochemical analysis of cell lines derived from solid tumors. J Histochem Cytochem 49: 1369-1378 (2001). PubMed ID 11668190

194. Meyer C, MacLeod RAF, Quentmeier H, Janssen JWG, Coignet LJ, Dyer MJS, Drexler HG: Establishment of the B cell precursor acute lymphoblastic leukemia cell line MUTZ-5 carrying a (12;13) translocation. Leukemia 15: 1471-1474 (2001). PubMed ID 11516110

193. Quentmeier H, Drexler HG, Fleckenstein D, Zaborski M, Armstrong A, Sims JE, Lyman SD: Cloning of thymic stromal lymphopoietin (TSLP) and signaling mechanisms leading to proliferation. Leukemia 15: 1286-1292 (2001). PubMed ID 11480573

192. MacLeod RAF, Drexler HG: Cell banks detect false cell lines: Journals must act too. The Lancet Oncol 2: 467-468 (2001). PubMed ID 11905721

191. Master JR, Thompson JA, Daly-Burns B, Reid YA, Dirks WG, Packer P, Toji LH, Ohno T, Tanabe H, Arlett CF, Kelland LR, Harrison M, Virmani A, Ward TH, Ayres KL, Debenham PG: Short tandem repeat profiling provides an international reference standard for human cell lines. Proc Natl Acad Sci 98: 8012-8017 (2001). PubMed ID 11416159

190. Lamp EC, Drexler HG: Biology of tartrate-resistant acid phosphatase. Leukemia Lymphoma 39: 477-484 (2000). PubMed ID 11342331

189. Uphoff CC, Drexler HG: Biology of monocyte-specific esterase. Leukemia Lymphoma 39: 257-270 (2000).PubMed ID 11342306

188. MacLeod RAF, Drexler HG: Chapter 13: Authentication and characterization. in: Human Cell Culture, Vol. III - Cancer Cell Lines Part 3: Leukemias and Lymphomas (ed Masters JRW, Palsson BO), Kluwer Academic Pub, Dordrecht (2000), pp. 371-397.

187. Herbst H, Drexler HG: Chapter 12: CD30-positive anaplastic large cell lymphoma cell lines. in: Human Cell Culture, Vol. III - Cancer Cell Lines Part 3: Leukemias and Lymphomas (ed Masters JRW, Palsson BO), Kluwer Academic Pub, Dordrecht (2000), pp. 355-370.

186. Drexler HG: Chapter 8: Erythroid-megakaryocytic cell lines. in: Human Cell Culture, Vol. III - Cancer Cell Lines Part 3: Leukemias and Lymphomas (ed Masters JRW, Palsson BO), Kluwer Academic Pub, Dordrecht (2000), pp. 259-294.

185. Drexler HG: Chapter 7: Monocytic cell lines. in: Human Cell Culture, Vol. III - Cancer Cell Lines Part 3: Leukemias and Lymphomas (ed Masters JRW, Palsson BO), Kluwer Academic Pub, Dordrecht (2000), pp. 237-257.

184. Drexler HG: Chapter 6: Myelocytic cell lines. in: Human Cell Culture, Vol. III - Cancer Cell Lines Part 3: Leukemias and Lymphomas (ed Masters JRW, Palsson BO), Kluwer Academic Pub, Dordrecht (2000), pp. 207-236.

183. Drexler HG, Minowada J: Chapter 1: Human leukemia-lymphoma cell lines: Historical perspective, state of the art and future prospects. in: Human Cell Culture, Vol. III - Cancer Cell Lines Part 3: Leukemias and Lymphomas (ed Masters JRW, Palsson BO), Kluwer Academic Pub, Dordrecht (2000), pp. 1-18.

182. Drexler HG, Matsuo Y, MacLeod RAF: Continuous hematopoietic cell lines as model systems for leukemia-lymphoma research. Leukemia Res 24: 881-911 (2000). PubMed ID 11086173

181. MacLeod RAF, Fritze D: Cell Banks: A Service to Animal Cell Technology. Section: DSMZ: Department of Human and Animal Cell Cultures. in: The Encyclopedia of Cell Technology (eds Spier E, Griffiths B, Scragg AH), Wiley, New York, 2000, pp. 310-312.

180. MacLeod RAF, Spitzer D, Bar-Am I, Sylvester JE, Kaufmann M, Wernich A, Drexler HG: Karyotypic dissection of Hodgkińs disease cell lines reveals ectopic subtelomeres and ribosomal DNA at sites of multiple jumping translocations and genomic amplification. Leukemia 14: 1803-1814 (2000). PubMed ID 11021756

179. Quentmeier H, Dirks WG, Fleckenstein D, Zaborski M, Drexler HG: Tumor necrosis factor- -induced proliferation requires synthesis of granulocyte-macrophage colony-stimulating factor. Exp Hematol 28: 1008-1015 (2000). PubMed ID 11008013

178. Drexler HG, Gignac SM, Dirks WG, von Wasielewski R, Werner M: Pathobiology of NPM-ALK and variant fusion genes in anaplastic large cell lymphoma and other lymphomas. Leukemia 14: 1533-1559 (2000). PubMed ID 10994999

177. Drexler HG: The Leukemia-Lymphoma Cell Line FactsBook. Academic Press, London, 2000, 733 pages.

176. Steube KG, Meyer C, Drexler HG: Multiple regulation of constitutive and induced interleukin-8 secretion in human myelomonocytic cell lines. Cytokine 12: 1236-1239 (2000). PubMed ID 10930303

175. MacLeod RAF: Chapter 4.7: Rapid initiation of adherent monolayer cell cultures: The "cold cocktail" method. in: Cell and Tissue Culture for Medical Research (eds Doyle A, Griffiths JB), John Wiley, Chichester, England, 2000, pp. 224-234.

174. Drexler HG, Matsuo Y: Malignant hematopoietic cell lines: In vitro models for the study of multiple myeloma and plasma cell leukemia. Leukemia Res 24: 681-703 (2000). PubMed ID 10936422

173. Matsuo Y, Drexler HG, Nishizaki C, Harashima A, Fukuda S, Kozuka T, Sezaki T, Orita K: Human bone marrow stroma-dependent myeloma cell line MOLP-5 derived from a patient in leukaemic phase of multiple myeloma. Brit. J. Haematol. 109: 54-63 (2000). PubMed ID 10848782

172. Hu ZB, Drexler HG: Establishment of human leukaemia cell lines. in: Cell and Tissue Culture for Medical Research (eds Doyle A, Griffiths JB), John Wiley, Chichester, England, 2000, pp. 205-218.

171. Drexler HG, Uphoff CC: Contamination of cell cultures, mycoplasma. in: The Encyclopedia of Cell Technology (eds Spier E, Griffiths B, Scragg AH), Wiley, New York, 2000, pp. 609-627.

170. Drexler HG, Matsuo Y: Malignant hematopoietic cell lines: In vitro models for the study of natural killer cell leukemia-lymphoma cell lines. Leukemia 14: 777-782 (2000). PubMed ID 10803505

169. Janssen JWG, Vaandrager JW, Heuser T, Jauch A, Kluin PM, Geelen E, Bergsagel PL, Kuehl WM, Drexler HG, Otsuki T, Bartram CR, Schuuring E: Concurrent activation of a novel putative transforming gene, myeov, and cyclin D1 in a subset of multiple myeloma cell lines with t(11;14)(q13;q32). Blood 95: 2691-2698 (2000). PubMed ID 10753852

168. Steube KG, Meyer C, Drexler HG: Induction and secretion of the chemokines interleukin-8 and monocyte chemotactic protein-1 in human immature leukemia cell lines. Mol Cell Biol Res Commun 3: 60-65 (2000). PubMed ID 10683319

167. Fleckenstein E, Dirks WG, Drexler HG: The human tartrate-resistant acid phosphatase (TRAP): Involvement of the hemin responsive elements (HRE) in transcriptional regulation. Leukemia Lymphoma 36: 603-612 (2000). PubMed ID 10784406

166. Stacey GN, Masters JRW, Hay RJ, Drexler HG, MacLeod RAF, Freshney RI: Cell contamination leads to inaccurate data: We must take action now. Nature 403: 356 (2000).

165. Drexler HG, Fombonne S, Matsuo Y, Hu ZB, Hamaguchi H, Uphoff CC: p53 alterations in human leukemia-lymphoma cell lines: In vitro artifact or prerequisite for cell immortalization? Leukemia 14: 198-206 (2000). PubMed ID 10637496

164. Drexler HG: Malignant hematopoietic cell lines: In vitro models for the study of myelodysplastic syndromes. Leukemia Res 24: 109-115 (2000). PubMed ID 10654445

163. Uphoff CC, Drexler HG: Detection of mycoplasma contamination in cell cultures by PCR analysis. Human Cell 12: 229-236 (1999). PubMed ID 10834110

162. Matsuo Y, Nishizaki C, Drexler HG: Efficient DNA fingerprinting method for the identification of cross-culture contamination of cell lines. Human Cell 12: 149-154 (1999). PubMed ID 10695022

161. Bohnenstengel FI, Steube KG, Meyer C, Quentmeier H, Nugroho BW, Proksch P: 1H-Cyclopenta[b]benzofuran lignans from Aglaia species inhibit cell proliferation and alter cell cyle distribution in human monocytic leukemia cell lines. Z. Naturforsch. 54c: 1075-1083 (1999). PubMed ID 10685499

160. Dirks WG, MacLeod RAF, Drexler HG: ECV304 (endothelial) is really T24 (bladder carcinoma): Cell line cross-contamination at source. In Vitro Cell Dev Biol 35: 558-559 (1999). PubMed ID 10614862

159. Matsuo Y, Drexler HG, Takeuchi M, Orita K: Novel B-cell precursor leukemia sister cell lines, NALM-33 and NALM-34, established from a patient with acute lymphoblastic leukemia. Leukemia Lymphoma 35: 513-526 (1999). PubMed ID 10609789

158. Knecht H, Berger C, McQuain C, Rothenberger S, Bachmann E, Martin J, Esslinger C, Drexler HG, Cai YC, Quesenberry PJ, Odermatt J: Latent membrane protein 1 associated signaling pathways are important in tumor cells of Epstein-Barr virus negative Hodgkin's disease. Oncogene 18: 7161-7167 (1999). PubMed ID 10597317

157. Uphoff CC, Habig S, Fombonne S, Matsuo Y, Drexler HG: ABL-BCR expression in BCR-ABL-positive human leukemia cell lines. Leukemia Res 23: 1055-1060 (1999). PubMed ID 10576511

156. MacLeod RAF, Dirks WG, Kaufmann M, Matsuo Y, Milch H, Drexler HG: Widespread intraspecies cross-contamination of human tumor cell line arising at source. Int J Cancer 83: 555-563 (1999). PubMed ID 10508494

155. Dirks W, MacLeod RAF, Jäger K, Milch H, Drexler HG: First searchable database for DNA profiles of human cell lines: Sequential use of fingerprint techniques for authentication. Cell Mol Biol 45: 841-853 (1999). PubMed ID 10541480

154. Drexler HG, Dirks WG, MacLeod RAF: False human hematopoietic cell lines: Cross-contaminations and misinterpretations. Leukemia 13: 1601-1607 (1999). PubMed ID 10516762

153. Eder C, Steube KG, Proksch P, Wray V, Bringmann G, van Soest RWM, Sudarsono S, Ferdinandus E, Pattisina LA, Wiryowidagdo, Moka W: New alkaloids from the indopacific sponge stylissa carteri. J Nat Prod 62: 184-187 (1999). PubMed ID 9917317

152. Marini P, MacLeod RAF, Treuner C, Bruchelt G, Bohm W, Wolburg H, Schweizer P, Girgert R: SiMa, a new neuroblastoma cell line combining poor prognostic cytogenetic markers with high adrenergic differentiation. Cancer Genet Cytogenet 112: 161-164 (1999). PubMed ID 10686945

151. Steube KG, Meyer C, Drexler HG: Constitutive protein expression of monocyte chemotactic protein-1 (MCP-1) by myelomonocytic cell lines and regulation of the secretion by anti- and proinflammatory stimuli. Leukemia Res 23: 843-849 (1999). PubMed ID 10475624

150. Matsuo Y, Drexler HG, Takeuchi M, Orita K: A novel biphenotypic B-cell precursor leukemia cell line (NALM-29) carrying t(9;22)(q34;q11) established from a patient with acute leukemia. Leukemia Res 23: 731-740 (1999). PubMed ID 10456671

149. Drexler HG, Matsuo Y: Guidelines for the characterization and publication of human malignant hematopoietic cell lines. Leukemia 13: 835-842 (1999). PubMed ID 10360369

148. Dirks W, Rome D, Ringel F, Jäger K, MacLeod RAF, Drexler HG: Expression of the growth arrest-specific gene (GAS6) in leukemia and lymphoma cell lines. Leukemia Res 23: 643-651 (1999). PubMed ID 10400186

147. Steube KG, Meyer C, Drexler HG: Constitutive secretion of hematopoietic cytokines by human carcinoma cell lines and its up-regulation by interleukin-1 and phorbol ester. Oncol Rep 6: 427-432 (1999). PubMed ID 10023015

146. Matsuo Y, Sugimoto A, Harashima A, Nishizaki C, Drexler HG, Orita K: Myeloperoxidase positive acute lymphoblastic leukemia cell lines, NALM-30, NALM-31 and NALM-32, carrying Philadelphia chromosome with biphenotypic characteristics. Human Cell 11: 221-230 (1999). PubMed ID 10363160

145. Drexler HG, Meyer C, Gaidano G, Carbone A: Constitutive cytokine production by primary effusion (body cavity-based) lymphoma-derived cell lines. Leukemia 13: 634-640 (1999). PubMed ID 10214873

144. Steube KG, Meyer C, Habig S, Uphoff CC, Drexler HG: Expression of receptor tyrosine kinase HTK (hepatoma transmembrane kinase) and HTK ligand by human leukemia-lymphoma cell lines. Leukemia Lymphoma 33: 371-376 (1999). PubMed ID 10221518

143. Bohnenstengel FI, Steube KG, Meyer C, Nugroho BW, Hung PD, Kiet LC, Proksch P: Structure activity relationships of antiproliferative rocaglamide derivatives from Aglaia species (Meliaceae). Z Naturforsch 54c: 55-60 (1999). PubMed ID 10223787

142. Drexler HG, Meyer C, Quentmeier H: Effects of FLT3 ligand on proliferation and survival of myeloid leukemia cells. Leukemia Lymphoma 33: 83-91 (1999). PubMed ID 10194124

141. Drexler HG, MacLeod RAF, Uphoff CC: Leukemia cell lines: In vitro models for the study of Philadelphia chromosome-positive leukemia. Leukemia Res 23: 207-215 (1999). PubMed ID 10071072

124. Steube KG, Meyer C, Proksch P, Supriyono A, Sumaryono W, Drexler HG: A new calyculin derivative from the sponge Theonella swinhoei is a novel and potent inhibitor of tumor cell proliferation. Anticancer Res 18: 129-138 (1998). PubMed ID 9568067

123. Eder C, Schupp P, Proksch P, Wray V, Steube KG, Müller C, van Soest RWM: Bioactive pyridoacridine alkaloids from the micronesian sponge Oceanapia sp.. J Nat Prod 61: 301-305 (1998). PubMed ID 9514015

122. Steube KG, Meyer C, Tachibana M, Murai M, Drexler HG: Bladder carcinoma cell line KU-19-19-derived cytokines support proliferation of growth factor-dependent hematopoietic cell lines: Modulation by phorbol ester, interferon-gamma and interleukin-1ß. Biochem Biophys Res Commun 242: 497-501 (1998). PubMed ID 9464244

121. Matsuo Y, MacLeod RAF, Kojima K, Kuwahara K, Sakata A, Drexler HG, Nishizaki C, Fukuda S, Inoue Y, Sezaki T, Sakaguchi N, Orita K: A novel ALL-L3 cell line, BALM-16, lacking expression of immunoglobulin chains derived from a patient with hypercalcemia. Leukemia 11: 2168-2174 (1997). PubMed ID 9447837

120. MacLeod RAF, Dirks WG, Reid YA, Hay RJ, Drexler HG: Identity of original and late late-passage Dami megakaryocytes with HEL erythroleukemia cells shown by combined cytogenetics and DNA fingerprinting. Leukemia 11: 2032-2038 (1997). PubMed ID 9447816

119. Drexler HG, Zaborski M, Quentmeier H: Trombopoietin supports the continuous growth of cytokine-dependent human leukemia cell lines. in: Acute Leukemias VII (ed Hiddemann W et al), Springer, Berlin (1997), pp. 379-386.

118. Uphoff CC, MacLeod RAF, Denkmann SA, Golub TR, Borkhardt A, Janssen JWG, Drexler HG: Occurrence of TEL-AML1 fusion resulting from t(12;21) translocation in human early B-lineage leukemia cell lines. in: Acute Leukemias VII (ed Hiddemann W et al), Springer, Berlin (1997), pp. 234-241.

117. Bredoux C, Uphoff CC, Drexler HG: Expression of tie receptor tyrosine kinase in leukemia cell lines. in: Acute Leukemias VII (ed Hiddemann W et al), Springer, Berlin (1997), pp. 199-205.

116. MacLeod RAF, Dirks WG, Drexler HG: Early contamination of the Dami cell line by HEL. Blood 90: 2850-2851 (1997). PubMed ID 9326259

115. Drexler HG, Zaborski M, Quentmeier H: Interferon-gamma induced proliferation of human myeloid leukaemia cell lines. Brit J Haematol 98: 699-710 (1997). PubMed ID 9332328

114. Bredoux C, Uphoff CC, Drexler HG: Expression of tie receptor tyrosine kinase in human leukemia cell lines. Leukemia Res 21: 595-601 (1997). PubMed ID 9301679

113. Matsuo Y, MacLeod RAF, Uphoff CC, Drexler HG, Nishizaki C, Katayama Y, Kimura G, Fujii N, Omoto E, Harada M, Orita K: Two acute monocytic leukemia (AML-M5a) cell lines (MOLM-13 and MOLM-14) with interclonal phenotypic heterogeneity showing MLL-AF9 fusion resulting from an occult chromosome insertion, ins(11;9)(q23;p22p23). Leukemia 11: 1469-1477 (1997). PubMed ID 9305600

112. Karawajew L, Wuchter C, Ruppert V, Drexler H, Gruss HJ, Dörken B, Ludwig WD: Differential CD95 expression and function in T and B lineage acute lymphoblastic leukemia cells. Leukemia 11: 1245-1252 (1997). PubMed ID 9264377

111. Steube K, Gignac SM, Hu ZB, Teepe D, Harms D, Kabisch H, Gaedicke G, Hansen-Hagge T, MacLeod RAF, Quentmeier H, Drexler HG: In vitro culture studies of childhood myelodysplastic syndrome: Establishment of cell line MUTZ-1. Leukemia Lymphoma 25: 345-363 (1997). PubMed ID 9168445

110. Quentmeier H, Zaborski M, Drexler HG: The human bladder carcinoma cell line 5637 constitutively secretes functional cytokines. Leukemia Res 21: 343-350 (1997). PubMed ID 9150352

109. Steube KG, Teepe D, Meyer C, Zaborski M, Drexler HG: A model system in haematology and immunology: The human monocytic cell line MONO-MAC-1. Leukemia Res 21: 327-335 (1997). PubMed ID 9150350

108. Drexler HG, Zaborski M, Quentmeier H: Cytokine response profiles of human myeloid factor-dependent human leukemia cell lines. Leukemia 11: 701-709 (1997). PubMed ID 9180295

107. Drexler HG, Zaborski M, Quentmeier H: Thrombopoietin supports the continuous growth of cytokine-dependent human leukemia cell lines. Leukemia 11: 541-551 (1997). PubMed ID 9096695

106. Drexler HG, Quentmeier H: Use of human leukemia-lymphoma cell lines in hematological research: Effects of thrombopoietin on human leukemia cell lines. Human Cell 9: 309-316 (1997). PubMed ID 9183663

105. Dirks W, Schöne S, Uphoff C, Quentmeier H, Pradella S, Drexler HG: Expression and function of CD95 (FAS/APO-1) in leukemia-lymphoma tumour lines. Brit J Haematol 96: 584-593 (1997). PubMed ID 9054667

104. Uphoff CC, MacLeod RAF, Denkmann SA, Golub TR, Borkhardt A, Janssen JWG, Drexler HG: Occurrence of TEL-AML1 fusion resulting from (12;21) translocation in human early B-lineage leukemia cell lines. Leukemia 11: 441-447 (1997). PubMed ID 9067587

103. Meierhoff U, Dehmel U, Gruss HJ, Dirks W, Drexler HG: Expression of FLT3 and FLT3-ligand in human leukemia-lymphoma cell lines. in: Acute Leukemias VI (ed Büchner T et al), Springer, Berlin (1997), pp. 185-192.

102. Fleckenstein E, Drexler HG: Tartrate-resistant acid phosphatase: Gene structure and function. Leukemia 11: 10-13 (1997). PubMed ID 9001411


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101. MacLeod RAF, Buchheim T, Kaufmann M, Drexler HG: Chromosomal breakage correlates with delayed cell killing in normal and ataxia teleangiectasia cell lines treated with bleomycin. Mutation Res 372: 33-42 (1996). PubMed ID 9003529

100. Rosnet O, Bühring HJ, deLapeyriere O, Beslu N, Lavagna C, Marchetto S, Rappold I, Drexler HG, Birg F, Rottapel R, Hannum C, Dubreuil P, Birnbaum D: Expression and signal transduction of the FLT3 tyrosine kinase receptor. in: Molecular Biology of Hematopoiesis 5 (eds Abraham NG et al), Plenum Press, New York (1996), pp. 361-367.

99. Graf G, Zaborski M, Quentmeier H, Drexler HG: Phorbol ester PMA induces expression of the thrombopoietin receptor MPL in leukemia cells. Leukemia Lymphoma 24: 149-157 (1996). PubMed ID 9049971

98. Quentmeier H, Duschl A, Hu ZB, Schnarr B, Zaborski M, Drexler HG: MUTZ-3, a monocytic model cell line for interleukin-4 and lipopolysaccharide studies. Immunology 89: 606-612 (1996). PubMed ID 9014829

97. Graf G, Dehmel U, Drexler HG: Expression of thrombopoietin and thrombopoietin receptor MPL in human leukemia-lymphoma and solid tumor cell lines. Leukemia Res 20: 831-838 (1996). PubMed ID 8960108

96. Knecht H, McQuain C, Martin J, Rothenberger S, Drexler HG, Berger C, Bachmann E, Kittler ELW, Odermatt BF, Quesenberry PJ: Expression of the LMP1 oncoprotein in the EBV negative Hodgkin´s disease cell line L-428 is associated with Reed-Sternberg cell morphology. Oncogene 13: 947-953 (1996). PubMed ID 8806684

95. Drexler HG, Quentmeier H: Thrombopoietin: Expression of its receptor MPL and proliferative effects on leukemic cells. Leukemia 10: 1405-1421 (1996). PubMed ID 8751457

94. MacLeod RAF, Hu ZB, Kaufmann M, Drexler HG: Cohabiting t(12;22) and inv(3) primary rearrangements in an acute myelomonocytic leukemia (FAB M4) cell line. Genes Chromosomes Cancer 16: 144-148 (1996). PubMed ID 8818662

93. Hu ZB, Ma W, Zaborski M, MacLeod RAF, Quentmeier H, Drexler HG: Establishment and characterization of two novel cytokine-responsive acute myeloid and monocytic leukemia cell lines, MUTZ-2 and MUTZ-3. Leukemia 10: 1025-1040 (1996). PubMed ID 8667638

92. Rosnet O, Bühring HJ, deLapeyriere O, Beslu N, Lavagna C, Marchetto S, Rappold I, Drexler HG, Birg F, Rottapel R, Hannum C, Dubreuil P, Birnbaum D: Expression and signal transduction of the FLT3 tyrosine kinase receptor. Acta Haematol 95: 218-223 (1996). PubMed ID 8677746

91. Challier CS, Uphoff CC, Janssen JWG, Drexler HG: Differential expression of the UFO oncogene in human leukemia-lymphoma cell lines. Leukemia 10: 781-787 (1996). PubMed ID 8656672

90. Gignac SM, Hu ZB, Denkmann SA, Uphoff CC, Drexler HG: Esterase isoenzyme profiles of 255 leukemia-lymphoma cell lines from all hematopoietic cell lineages. Leukemia Lymphoma 22: 143-151 (1996). PubMed ID 8724542

89. Fleckenstein E, Dirks W, Dehmel U, Drexler HG: Cloning and characterization of the human tartrate-resistant acid phosphatase (TRAP) gene. Leukemia 10: 637-643 (1996). PubMed ID 8618440

88. Drexler HG: Expression of FLT3 receptor and response to FLT3 ligand by leukemia cells . Leukemia 10: 588-599 (1996). PubMed ID 8618433

87. Quentmeier H, Zaborski M, Graf G, Ludwig WD, Drexler HG: Expression of the receptor MPL and proliferative effects of its ligand thrombopoietin on human leukemia cell lines. Leukemia 10: 297-310 (1996). PubMed ID 8637239

86. Dehmel U, Quentmeier H, Drexler HG: Effects of FLT3 ligand on human leukemia cells. II. Agonistic and antagonistic effects of other cytokines. Leukemia 10: 271-278 (1996). PubMed ID 8637236

85. Dehmel U, Zaborski M, Meierhoff G, Rosnet O, Birnbaum D, Ludwig WD, Quentmeier H, Drexler HG: Effects of FLT3 ligand on human leukemia cells. I. Proliferative response of myeloid leukemia cells. Leukemia 10: 261-270 (1996). PubMed ID 8637235

84. Dirks W, Nolte M, Werner M, Jäger K, Koch C, Drexler HG: Preservation of functional and regulatory domains of expressed bcl-2 genes in non-Hodgkin's lymphomas. Leukemia 10: 50-158 (1996). PubMed ID 8558921

83. Dirks WG, Zaborski M, Jäger K, Challier C, Shiota M, Quentmeier H, Drexler HG: The (2;5)(p23;q35) translocation in cell lines derived from malignant lymphomas: Absence of t(2;5) in Hodgkin-analogous cell lines. Leukemia 10: 142-149 (1996). PubMed ID 8558920

82. Verschuren MCM, Comans-Bitter WM, Mason DY, Drexler HG, Van Dongen JJM: Expression of mb1 and B29 proteins in human hemapoietic malignancies and cell lines. in: Leukocyte Typing V. White Cell Differentiation Antigens (eds Schlossman SF et al), Oxford University Press, Oxford (1995), pp. 677-679.

81. Drexler HG, Quentmeier H, MacLeod RAF, Uphoff CC, Hu ZB: Leukemia cell lines: In vitro models for the study of acute promyelocytic leukemia. Leukemia Res 19: 681-691 (1995). PubMed ID 7500643

80. Hassan HT, Drexler HG: Interleukins and colony stimulating factors in human myeloid leukemia cell lines. Leukemia Lymphoma 20: 1-15 (1995). PubMed ID 8750618

79. Drexler HG, Borkhardt A, Janssen JWG: Detection of chromosomal translocations in leukemia-lymphoma cells by polymerase chain reaction. Leukemia Lymphoma 19: 359-380 (1995). PubMed ID 8590836

78. Burgstahler R, Kempkes B, Steube K, Lipp M: Expression of the chemokine receptor BLR2/EBI1 is specifically transactivated by Epstein-Barr virus nuclear antigen 2. Biochem Biophys Res Commun 215: 737-743 (1995). PubMed ID 7488016

77. Steube KG, Jadau A, Teepe D, Drexler HG: Expression of the bcl-2 mRNA and protein in leukemia-lymphoma cell lines. Leukemia 9: 1841-1846 (1995). PubMed ID 7475272

76. Steube K, Drexler HG: The protein kinase C activator Bryostatin-1 induces the rapid release of TNF from MONO-MAC-6 cells. Biochem. Biophys. Res. Commun. 214: 1197-1203 (1995). PubMed ID 7575530

75. Meierhoff G, Dehmel U, Gruss HJ, Rosnet O, Birnbaum D, Quentmeier H, Dirks W, Drexler HG: Expression of FLT3 receptor and FLT3-ligand in human leukemia-lymphoma cell lines. Leukemia 9: 1368-1372 (1995). PubMed ID 7643626

74. Drexler HG, MacLeod RAF, Borkhardt A, Janssen JWG: Recurrent chromosomal translocations and fusion genes in leukemia-lymphoma cell lines. Leukemia 9: 480-500 (1995). PubMed ID 7885046

73. Quentmeier H, Kolsdorf K, Zaborski M, Drexler HG: IL-4R and chain expression in LPS- and IL-4-stimulated MONO-MAC-6 cells. Leukemia 9: 336-340 (1995). PubMed ID 7532769

72. Steube KG, Grunicke D, Drexler HG: Isoenzyme analysis as a rapid method for the examination of the species identity of cell cultures. In Vitro Cell Dev Biol 31A: 115-119 (1995). PubMed ID 7735563


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71. Drexler HG, Gignac SM, Minowada J: Chapter: Hematopoietic Cell Lines. in: Atlas of Human Tumor Cell Lines (eds Hay RJ, Gazdar R, Park JG), Academic Press, Orlando, 1994, pp. 213-250.

70. Hu ZB, Drexler HG: Chapter: Establishment of Human Leukemia Cell Lines. in: Cell & Tissue Culture: Laboratory Procedures (eds Griffiths JB, Doyle A, Newell DG), John Wiley, Chichester (1994), pp. 21C: 1.1-1.11.

69. Drexler HG: Recent results on the biology of Hodgkin and Reed-Sternberg cells. II. Continuous cell lines. in: Leukemia & Lymphoma Reviews 3 (ed Polliack A), Harwood, Chur (1994), pp. 201-225.

68. Drexler HG: Recent results on the biology of Hodgkin and Reed-Sternberg cells. I. Biopsy Material. in: Leukemia & Lymphoma Reviews 3 (ed Polliack A), Harwood, Chur (1994), pp. 169-199.

67. Schardt C, Schardt C, Drexler HG, Ganser A, Hoelzer D: Regulation of the expression of ICAM-1 on pre B-cell lines by TNA- and IFN-. in: Acute Leukemias IV (ed Büchner T et al), Springer, Berlin (1994), pp. 85-89.

66. Ludwig WD, Harbott J, Rieder H, Bartram CR, Maurer J, Becher R, Heine B, Gassmann W, Drexler HG, Martin M, Sperling C, Völkers B, Reiter A, Ritter J, Hiddemann W, Büchner T, Löffler H, Fonatsch C, Hoelzer D, Riehm H, Thiel E: Incidence, biologic features and treatment outcome of myeloid-antigen-positive acute lympholastic leukemia (My+ ALL). in: Acute Leukemias IV (ed Büchner T et al), Springer, Berlin (1994), pp. 24-32.

65. Gruss HJ, Herrmann F, Drexler HG: Hodgkin's disease: A cytokine-producing tumor - a review. Crit Rev Oncogenesis 5: 473-538 (1994). PubMed ID 8519809

64. Gruss HJ, DaSilva N, Hu ZB, Uphoff CC, Goodwin RG, Drexler HG: Expression and regulation of CD30 ligand and CD30 in human leukemia-lymphoma cell lines. Leukemia 8: 2083-2094 (1994). PubMed ID 7528856

63. Drexler HG: Leukemia cell lines: In vitro models for the study of chronic myeloid leukemia. Leukemia Res 18: 919-927 (1994). PubMed ID 7996873

62. Quentmeier H, Kolsdorf K, Zaborski M, Drexler HG: IL-4 inhibits the LPS-induced expression of CD14 and monocyte-specific esterase mRNA in MONO-MAC-6 cells. Leukemia 8: 1551-1556 (1994). PubMed ID 7522293

61. Uphoff CC, Hu ZB, Gignac SM, Ma W, Rainey FA, Kreutz M, Ludwig WD, Drexler HG: Characterization of the monocyte-specific esterase (MSE) gene. Leukemia 8: 1510-1526 (1994). PubMed ID 8090031

60. Fleckenstein E, Uphoff CC, Drexler HG: Effective treatment of mycoplasma contamination in cell lines with enrofloxazin (Baytril). Leukemia 8: 1424-1434 (1994). PubMed ID 7520103

59. MacLeod RAF, Voges M, Bryant PE, Drexler HG: Chromatid aberration dose responses and dispersal in human G2 lymphocytes treated with bleomycin: Comparison with equivalent X-irradiation reveals formation of a novel class of heavily damaged cells. Mutation Res 309: 73-81 (1994). PubMed ID 7519735

58. Drexler HG, Gignac SM, Hu ZB, Hopert A, Fleckenstein E, Voges M, Uphoff CC: Treatment of mycoplasma contamination in a large panel of cell cultures. In Vitro Cell Dev Biol 30A: 344-347 (1994). PubMed ID 8069460

57. Steube KG, Grunicke D, Drexler HG: Different biological effects of the two protein kinase C activators bryostatin-1 and TPA on human carcinoma cell lines. Invest New Drugs 12: 15-23 (1994). PubMed ID 7960600

56. DaSilva N, Hu ZB, Ma W, Rosnet O, Birnbaum D, Drexler HG: Expression of the FLT3 gene in human leukemia-lymphoma cell lines. Leukemia 8: 885-888 (1994). PubMed ID 8182945

55. Quentmeier H, Schumann-Kindel G, Mühlradt PF, Drexler HG: Induction of proto-oncogene and cytokine expression in human peripheral blood monocytes and the monocytic cell line THP-1 after stimulation with mycoplasma-derived material MDHM. Leukemia Res 18: 319-325 (1994). PubMed ID 8182922

54. Hu ZB, Ma W, Uphoff CC, Quentmeier H, Drexler HG: c-kit expression in megakaryoblastic leukemia cell lines. Blood 83: 2133-2144 (1994). PubMed ID 7512841

53. Drexler HG, Gignac SM: Characterization and expression of tartrate-resistant acid phosphatase (TRAP) isoenzyme in hematopoietic cells. Leukemia 8: 359-368 (1994). PubMed ID 8127141

52. Ma W, Hu ZB, Drexler HG: Sensitivity of different methods for the detection of myeloperoxidase in leukemia cells. Leukemia 8: 336-342 (1994). PubMed ID 8309258

51. Muller-Bérat N, Minowada J, Tsuji-Takayama K, Drexler HG, Lanotte M, Wieslander J, Wiik A: The phylogeny of proteinase 3/myeloblastin, the autoantigen in Wegener's granulomatosis, and myeloperoxidase as shown by immunohistochemical studies on human leukemic cell lines. Clin Immunol Immunopathol 70: 51-59 (1994).

50. MacLeod RAF: Chapter: Rapid Monolayer Primary Cell Culture: The "Cold Cocktail" Method. in: Cell & Tissue Culture: Laboratory Procedures (eds Griffiths JB, Doyle A, Newell DG), John Wiley, Chichester (1993), pp. 3E: 2.1-2.8.

49. Gignac SM, Quentmeier H, Brauer S, Hoffbrand AV, strong>Drexler HG: Acid phosphatase isoenzyme profiles in acute and chronic leukemias. in: Leukemia & Lymphoma Reviews 2 (ed Polliack A), Harwood, Chur (1993), pp. 159-170.

48. Pietsch T, Kyas U, Drexler H.G., Welte K: Human stem cell factor is a growth factor for myeloid leukemia cells. In: Recent Results in Cancer Research, Vol. 131. Recent Advances in Cell Biology of Acute Leukemia. Impact on Clinical Diagnosis and Therapy (eds Ludwig WD, Thiel E), Springer, Heidelberg (1993), pp. 329-338. PubMed ID 7692572

47. Drexler HG, Ludwig WD: Incidence and clinical relevance of myeloid antigen-positive acute lymphoblastic leukemia. In: Recent Results in Cancer Research, Vol. 131. Recent Advances in Cell Biology of Acute Leukemia. Impact on Clinical Diagnosis and Therapy (eds Ludwig WD, Thiel E), Springer, Heidelberg (1993), pp. 53-66. PubMed ID 8210659

46. Hopert A, Uphoff CC, Wirth M, Hauser H, Drexler HG: Mycoplasma detection by PCR analysis. In Vitro Cell Dev Biol 29A: 819-821 (1993). PubMed ID 8118618

45. Drexler HG, Häne B, Hu ZB, Uphoff CC: HeLa cross-contamination of a leukemia cell line. Leukemia 7: 2077-2078 (1993). PubMed ID 8305077

44. Nuthmann V, Dirks W, Drexler HG: Transient expression of tartrate-resistant acid phosphatase (TRAP) gene in hamster cells: A pilot study. Leukemia 7: 1960-1964 (1993). PubMed ID 7504771

43. Verschuren MCM, Comans-Bitter WM, Kapteijn CAC, Mason DY, Brouns GS, Borst JG, Drexler HG, Van Dongen JJN: Transcription and protein Expression of mb-1 and B29 genes in human hematopoietic malignancies and cell lines. Leukemia 7: 1939-1947 (1993). PubMed ID 8255092

42. Hu ZB, Ma WL, Uphoff CC, Lanotte M, Drexler HG: Modulation of gene expression in the acute promyelocytic leukemia cell line NB4. Leukemia 7: 1817-1823 (1993). PubMed ID 7901456

41. Hu ZB, Ma W, Uphoff CC, Drexler HG: Expression and modulation of annexin VIII in human leukemia-lymphoma cell lines. Leukemia Res 17: 949-957 (1993). PubMed ID 8231235

40. Häne BG, Jäger K, Drexler HG: The Pearson product-moment correlation coefficient is better suited for identification of DNA fingerprint profiles than band matching algorithms. Electrophoresis 14: 967-972 (1993). PubMed ID 8125064

39. Häne BG, Drexler HG: Retrovirus tests of human leukemia/lymphoma cell lines at DSM. Leukemia Lymphoma 11: 293-298 (1993). PubMed ID 7505150

38. Drexler HG, Sperling C, Ludwig WD: Terminal deoxynucleotidyl transferase (TdT) expression in acute myeloid leukemia: Incidence, biology, pathophysiology and prognosis. Leukemia 7: 1142-1150 (1993). PubMed ID 7688837

37. Steube KG, Grunicke D, Quentmeier H, Drexler HG: Different effects of the two protein kinase C activators bryostatin-1 and TPA on growth and differentiation of human monocytic leukemia cell lines. Leukemia Res 17: 897-901 (1993). PubMed ID 8412301

36. MacLeod RAF, Voges M, Drexler HG: MONO MAC 6: A mature monoblastic leukemia cell line with t(9;11)(p21;q23). Blood 82: 3221-3222 (1993). PubMed ID 7695659

35. Hu ZB, Ma W, Uphoff CC, Metge K, Gignac SM, Drexler HG: Myeloperoxidase: Expression and modulation in a large panel of human leukemia-lymphoma cell lines. Blood 82: 1599-1607 (1993). PubMed ID 8395912

34. Hopert A, Uphoff CC, Wirth M, Hauser H, Drexler HG: Specificity and sensitivity of polymerase chain reaction (PCR) in comparison with other methods for the detection of mycoplasma contamination in cell lines. J Immunol Methods 164: 91-100 (1993). PubMed ID 8360512

33. Gignac SM, Steube K, Schleithoff L, Janssen JWG, MacLeod RAF, Quentmeier H, Drexler HG: Multiparameter approach in the Identification of cross-contamined leukemia cell lines. Leukemia Lymphoma 10: 359-368 (1993). PubMed ID 8220135

32. Hu ZB, Gignac SM, Uphoff CC, Quentmeier H, Steube KG, Drexler HG: Induction of differentiation of human B-cell leukemia cell lines JVM-2 and EHEB by bryostatin 1. Leukemia Lymphoma 10: 135-142 (1993). PubMed ID 8374521

31. Metge K, Steube K, Uphoff CC, Gignac SM, Drexler HG: MDR1 expression in human leukemia-lymphoma cell lines. Leukemia 7: 896-897 (1993). PubMed ID 8099136

30. Drexler HG, Thiel E, Ludwig WD: Acute myeloid leukemias expressing lymphoid-associated antigens: Diagnostic incidence and prognostic significance. Leukemia 7: 489-498 (1993). PubMed ID 7681917

29. Hu ZB, Gignac SM, Quentmeier H, Pettit G, Drexler HG: Effects of dolastatins on human B-lymphocytic leukemia cell lines. Leukemia Res 17: 333-339 (1993). PubMed ID 8487581

28. Tasheva ES, Ariyasu T, Matsuo Y, Drexler HG, Minowada J: Possible new genetic marker for human lymphoid leukemias as detected by ribosomal protein S14 cDNA. Leukemia 7: 318-322 (1993). PubMed ID 8093911

27. Uphoff CC, Gignac SM, Metge K, Zschunke F, Radzun HJ, Drexler HG: Expression of the monocyte-specific esterase gene in leukemia-lymphoma cell lines. Leukemia 7: 58-62 (1993). PubMed ID 8418380

26. Steube KG, Drexler HG: Differentiation and growth modulation of myeloid leukemia cells by the protein kinase C activating agent Bryostatin-1. Leukemia Lymphoma 9: 141-148 (1993). PubMed ID 8477194

25. Drexler HG: Recent results on the biology of Hodgkin and Reed-Sternberg cells. II. Continuous cell lines. Leukemia Lymphoma 9: 1-26 (1993). PubMed ID 7682880


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24. MacLeod RAF: DNA fingerprinting of cell lines. Nature 359: 681-682 (1992).

23. MacLeod RAF, Häne B, Drexler HG: Cells, lines and DNA fingerprinting. In Vitro Cell Dev Biol 28: 591-592 (1992). PubMed ID 1429361

22. Uphoff CC, Drexler HG: Zellinien in Forschung und Technik In Vitro Systeme 7: 1-3 (1992).

21. Drexler HG: TdT-positive ALL-L3. Am J Clin Pathol 97: 741-742 (1992).

20. Steube K, Quentmeier H, Pettit G, Pietsch T, Brauer S, Grunicke D, Gignac SM, Drexler HG: Inhibition of cellular proliferation by the natural peptides dolastatin 10 and dolastatin 15. in: Molecular Biology of Haematopoiesis, Volume 2 (eds Abraham NG et al), Intercept, Andover (1992), pp. 567-573.

19. Drexler HG, Gignac SM, Patel D, Scott CS: Lineage-specific monocytic esterase, a distinct marker for leukemias of monocytic origin: Cytochemical, isoenzymatic and biochemical features. in: Leukemia & Lymphoma Reviews 1 (ed Polliack A), Harwood, Chur (1992), pp.147-164.

18. Drexler HG: Recent results on the biology of Hodgkin and Reed-Sternberg cells. I. Biopsy Material. Leukemia Lymphoma 8: 283-313 (1992). PubMed ID 1337848

17. Drexler HG, Minowada J: Hodgkin's disease derived cell lines: A review. Human Cell 5: 42-53 (1992). PubMed ID 1419951

16. Quentmeier H, Klaucke J, Mühlradt PF, Drexler HG: Role of IL-6, IL-2 and IL-4 in the in vitro induction of cytotoxic T cells. J Immunol 149: 3316-3320 (1992). PubMed ID 1431108

15. Häne B, Tümmler M, Jäger K, Schleithoff L, Janssen JWG, Drexler HG: Differences in DNA fingerprints of continuous leukemia cell lines from different sources. Leukemia 6: 1129-1133 (1992). PubMed ID 1434794

14. Steube K, Grunicke D, Pietsch T, Gignac SM, Pettit GR, Drexler HG: Dolastatin 10 and dolastatin 15: Effects of two natural peptides on growth and differentiation of leukemia cells. Leukemia 6: 1048-1053 (1992). PubMed ID 1405759

13. Gignac SM, Uphoff CC, MacLeod RAF, Steube K, Voges M, Drexler HG: Treatment of mycoplasma-contaminated continuous cell lines with Mycoplasma Removal Agent (MRA). Leukemia Res 16: 815-822 (1992). PubMed ID 1326687

12. Gruss HJ, Brach MA, Drexler HG, Bonifer R, Mertelsmann RH, Herrmann F: Expression of cytokine genes, cytokine receptor genes, and transcription factors in Hodgkin and Reed-Sternberg cells. Cancer Res 52: 3353-3360 (1992). PubMed ID 1596893

11. Uphoff CC, Brauer S, Grunicke D, Gignac SM, MacLeod RAF, Quentmeier H, Steube K, Tümmler M, Voges M, Wagner B, Drexler HG: Sensitivity and specificity of five different mycoplasma detection assays. Leukemia 6: 335-341 (1992). PubMed ID 1375305

10. Uphoff CC, Gignac SM, Drexler HG: Mycoplasma contamination in human leukemia cell lines. II. Elimination with various antibiotics. J Immunol Methods 149: 55-62 (1992). PubMed ID 1316409

9. Uphoff CC, Gignac SM, Drexler HG: Mycoplasma contamination in human leukemia cell lines. I. Comparison of various detection methods. J Immunol Methods 149: 43-53 (1992). PubMed ID 1374779

8. Gruss HJ, Brach MA, Drexler HG, Bross KJ, Herrmann F: Interleukin-9 is expressed by primary and cultured Hodgkin and Reed-Sternberg cells. Cancer Res 52: 1026-1031 (1992). PubMed ID 1737332

7. Uphoff CC, Drexler HG: Die Deutsche Sammlung von Mikroorganismen und Zellkulturen: Abteilung "Menschliche und tierische Zellkulturen". ALTEX 9: 39-44 (1992).

6. Quentmeier H, Brauer S, Pettit GR, Drexler HG: Cytostatic effects of dolastatin 10 and dolastatin 15 on human leukemia cell lines. Leukemia Lymphoma 6: 245-250 (1992).

5. Drexler HG, Gignac SM, Brauer S, Quentmeier H: Different survival of continuous cell lines transported in live or frozen form. In Vitro Cell Dev Biol 27A: 841-842 (1991). PubMed ID 1748623

4. Gignac SM, Quentmeier H, Brauer S, Hoffbrand AV, Drexler HG: Acid phosphatase isoenzyme profiles in acute and chronic leukemias. Leukemia Lymphoma 5: 293-303 (1991).

3. Drexler HG, Thiel E, Ludwig WD: Review of the incidence and clinical relevance of myeloid antigen-positive acute lymphoblastic Leukemia. Leukemia 5: 637-645 (1991). PubMed ID 1886419

2. Gignac SM, Brauer S, Häne B, Quentmeier H, Drexler HG: Elimination of mycoplasma from infected leukemia cell lines. Leukemia 5: 162-165 (1991). PubMed ID 2020199

1. Drexler HG, Gignac SM, Patel D, Scott CS: Lineage-specific monocytic esterase, a distinct marker for leukemias of monocytic origin: Cytochemical, isoenzymatic and biochemical features. Leukemia Lymphoma 4: 295-312 (1991).


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