Characterization

Beside the considerable tests for quality and identity control we routinely perform further investigations on the characteristics of the cell lines from the public repository. Furthermore, we verify the expression of aberrantly expressed genes, e.g. fusion genes, genes with characteristic point mutations, amplifications and determine the immunophenotype of hematological cell lines by FACS. All these investigations contribute to our aim to elaborate individual characteristics which, of course, can also serve as authentication parameters of a given cell line. However, we are in no position to verify and further examine every possible aspect of a given cell line. Some basic characteristics of most cell lines have been described in the literature quoted. Additional papers have been published on each cell line that should be consulted to obtain a general overview of a cell line.

Certain characteristics claimed to be expressed by a cell line might not be found reproducibly on every subclone or even the seeding culture. We cannot be held responsible for claims made by other scientists in the literature regarding certain features of the cell lines that might not be identified on the cell culture we provide.