Nomenclature of Peptidoglycan Structures of Cross-Linkage Types A and B, with Examples of DSMZ Strains Having Specific Peptidoglycan Types

Type A of cross-linkage

Nomenclature Peptidoglycan structures DSM No.
Schumann (2011) Schleifer and Kandler (1972)
A11 A1α L-Lys-direct 7447, 9682, 9683, 9684, 9849, 12492, 12643, 20066, 20311, 20379, 20340, 20341, 20393, 20395, 20627
A11.gly A1α L-Lys-direct; α-carboxyl group of D-Glu substituted by Gly -
A11.pep A2 L-Lys peptide subunit 1790, 1605, 2786, 14234, 20030, 46257
A11.1 A3α L-Lys-Gly 6203, 6208, 6209, 14480, 14481, 14482, 20213, 20089, 20091, 20121, 20416, 20431, 20446
A11.2 A3α L-Lys-Gly5-6 4804, 4805, 4806, 4807, 4808, 4809, 6718, 7068, 7373, 7377, 14617, 20029, 20039, 20231, 20232, 20260, 20261, 20262, 20266, 20267, 20322, 20323, 20324, 20501, 20454, 20459, 20672, 20673, 20674, 20675, 20676, 20677, 20714, 20771
A11.3 A3α L-Lys-Gly2-4-L-Ser1-2-Gly 6717, 6732, 10656, 10657, 15096, 20036, 20037, 20038, 20042, 20044, 20316, 20359, 20373, 20228, 20229, 20263, 20264, 20265, 20325, 20326, 20327, 20328, 20329, 20330, 20597, 20608, 20609, 20610, 20723
A11.4 A3α L-Lys-L-Ala 9848, 13613, 20194, 20196, 20117, 20377, 20349, 20451, 20663, 20728, 20746
A11.5 A3α L-Lys-L-Ala2 5636, 5576, 5577, 5578, 5623, 6634, 6777, 6905, 8249, 8581, 8582, 8583, 20186, 20188, 20189, 20192, 20202, 20375, 20288, 20392, 20545, 20399, 20662, 20523, 20560, 20561, 20563, 20564, 20565, 20567, 20568, 20569, 20572, 20573, 20575, 20725, 20727
A11.6 A3α L-Lys-L-Ala3 348, 2981, 11630, 11925, 11926, 12219, 20068, 20124, 20371, 20376, 20380, 20383, 20259, 20409, 20478, 20479, 20559, 20576, 46222
A11.7 A3α L-Lys-L-Ala4 20032, 20033, 20319, 20320, 20321, 20447
A11.8 A3α L-Lys-L-Ala-Gly4-5 9930, 9931, 20352, 20345
A11.9 A3α L-Lys-L-Ala-L-Ala(L-Ser) 7378, 20566, 20770
A11.10 A3α L-Lys-L-Ala2-L-Ala(L-Ser) -
A11.11 A3α L-Lys(L-Orn)-L-Ala2-L-Ser 20220, 20222, 20224, 20438, 20439
A11.12 A3α L-Lys-L-Ala2-Gly-L-Ala 6783, 20064, 20385, 20684, 20685
A11.13 A3α L-Lys-L-Ala-L-Ser 20190, 20093, 20248, 20410
A11.14 A3α L-Lys-L-Ser 20102
A11.15 A3α L-Lys-L-Ala2-L-Ser -
A11.16 A3α L-Lys-L-Ala(L-Ser)-L-Ser 20257
A11.17 A3α L-Lys-L-Ala-L-Thr-L-Ala 419, 420, 4983, 20115, 20116, 20126, 20138
A11.18 A3α L-Lys-L-Ser-L-Ala 20252, 20686
A11.19 A3α L-Lys-L-Ser-L-Ser(L-Ala) 20255
A11.20 A3α L-Lys-L-Ser-L-Ala2 12221, 13734, 20014, 20187, 20193, 20200, 20240, 20241, 20484, 20343, 20346, 46216
A11.21 A3α L-Lys(L-Orn)-L-Ala(L-Ser)-L-Ala2 6489, 6490, 6491, 10140, 20104, 20105, 20434, 20435
A11.22 A3α L-Lys-L-Ser-L-Ala2-3; α-carboxyl group of D-Glu substituted by glycine amide 20127
A11.23 A3α L-Lys-L-Ser-L-Thr-L-Ala 342, 12829, 13065, 13066, 20119, 20120, 20125, 20136, 20144, 20161, 20389, 20390, 20407
A11.24 A3α L-Lys-L-Thr-Gly 13760, 20061, 20067, 20386, 20715, 20716
A11.25 A3α L-Lys-L-Thr-L-Ala 20381, 20443, 20646, 20562, 20742
A11.26 A3α L-Lys-L-Thr-L-Ala; α-carboxyl group of D-Glu substituted by alanine amide 20142
A11.27 A3α L-Lys-L-Thr-L-Ala2 5635, 13067, 20133
A11.28 A3α L-Lys-L-Thr-L-Ala3 20153, 20550
A11.29 A3α L-Lys-L-Thr-L-Ser(L-Ala) 5199, 20062, 20065, 20480, 20558, 20574
A11.30 A3α L-Lys-L-Thr-L-Ser-L-Ala2 -
A11.31 A4α L-Lys-D-Asp 2094, 2146, 2381, 3320, 4747, 4838, 4839, 4840, 4841, 4864, 4865, 4866, 4903, 5632, 5633, 5634, 5661, 6035, 5622, 5705, 5707, 5708, 5731, 5732, 6630, 7370, 7371, 7372, 7374, 9126, 9172, 10177, 10550, 10551, 10532, 10533, 11492, 11664, 12361, 12744, 12745, 13145, 13335, 13343, 13344, 13989, 14526, 14421, 20001, 20003, 20004, 20005, 20006, 20007, 20008, 20010, 20011, 20012, 20015, 20016, 20017, 20019, 20020, 20021, 20022, 20023, 20051, 20053, 20181, 20182, 20184, 20197, 20203, 20206, 20207, 20214, 20054, 20056, 20057, 20059, 20063, 20069, 20072, 20073, 20074, 20075, 20076, 20077, 20079, 20080, 20081, 20087, 20096, 20098, 20100, 20101, 20160, 20312, 20315, 20318, 20175, 20176, 20177, 20178, 20180, 20216, 20353, 20354, 20355, 20356, 20357, 20382, 20384, 20225, 20238, 20242, 20243, 20244, 20245, 20247, 20249, 20250, 20253, 20254, 20258, 20280, 20281, 20283, 20284, 20285, 20287, 20289, 20291, 20293, 20331, 20332, 20333, 20334, 20335, 20336, 20337, 20338, 20485, 20486, 20487, 20492, 20494, 20495, 20496, 20497, 20498, 20499, 20339, 20350, 20351, 20388, 20533, 20534, 20433, 20450, 20452, 20453, 20469, 20475, 20477, 20481, 20642, 20653, 20654, 20655, 20515, 20531, 20532, 20552, 20553, 20554, 20555, 20556, 20557, 20570, 20571, 20580, 20584, 20587, 20588, 20602, 20605, 20607, 20628, 20633, 20670, 20679, 20680, 20681, 20682, 20690, 20691, 20692, 20717, 20718, 20719, 20720, 20721, 20726, 20749
A11.32 A4α L-Lys(L-Orn)-D-Asp 6492, 6493, 6494, 6531, 6532, 6533, 10105, 10106, 20083, 20084, 20086, 20221, 20436
A11.33 A4α L-Lys-D-Glu 7454, 13280, 14506, 14507, 14504, 14505, 20549, 20581, 20747
A11.34 A4α L-Lys-L-Ala-D-Asp -
A11.35 A4α L-Lys-L-Ala-L-Glu 4640, 13068, 13069, 20122, 20123, 20168, 20413, 20647, 20648, 20579
A11.36 A4α L-Lys-L-Ser-D-Asp 11295
A11.37 A4α L-Lys-D-Ser-D-Asp 20106, 20155, 20424, 46215
A11.38 A4α L-Lys-D-Ser-D-Glu 20432
A11.39 A4α L-Lys-L-Ser2-D-Glu 20448
A11.40 A4α L-Lys-Gly-D-Glu 320, 2306, 2307, 14442
A11.41 A3α L-Lys-Gly-L-Ala3 14508
A11.42 A4α L-Lys-Gly-D-Asp 6633, 20183
A11.43 A4α L-Lys-D-Glu2 13884, 20317, 20547
A11.44 A3α L-Lys-Gly(L-Ser) 20445
A11.45 A4α L-Lys-L-Thr-D-Asp 20577
A11.46 A3α L-Lys-L-Ala-Gly-L-Ala2 20593
A11.47 A3α L-Lys-L-Ala-Gly; α-carboxyl group of D-Glu substituted by alanine amide 20767
A11.48 A4α L-Lys-L-Ser-D-Glu 10543, 10542, 12657, 20603
A11.49 A3α L-Lys-L-Ser-Gly 20622
A11.50 A3α L-Lys-L-Ala-Gly 6778
A11.51 A5α L-Lys-L-Lys-D-Glu 8576, 8577, 11076, 11077, 11078, 13483, 20595
A11.52 A5α L-Lys-L-Lys-D-Asp 43320
A11.53 A5α L-Lys-L-Ala-L-Lys-D-Glu 9151, 9152, 9153, 20594, 20630, 20639
A11.54 A4α L-Lys-L-Glu 12333, 12334, 14418, 14419, 20167, 20645
A11.55 A5α L-Lys(L-Orn)-L-Lys-D-Glu 9169
A11.56 A4α L-Lys-Gly-L-Glu 6686, 6687, 6723, 20541
A11.57 A4α L-Lys-L-Thr-D-Glu 14281, 43852, 46000, 46001, 46097
A11.58 A4α L-Lys-L-Ser-L-Glu 10493, 10494
A11.59 A4α L-Lys-L-Ala-D-Glu -
A11.60 A4α L-Lys-D-Asp; α-carboxyl group of D-Glu substituted by glycine 10495, 14235
A11.61 A3α L-Lys-L-Ala(L-Ser) 12493
A11.62 A3α L-Lys-L-Ala2-Gly2-3-L-Ala(Gly) 13988
A11.63 A3α L-Lys-L-Ala-Gly3, L-Ser0-1 -
A12.1 A3α'a L-Lys-Gly 20362, 20369, 20470, 20472
A12.2 A4α' L-Lys-D-Glu 7456, 20358, 20548, 20473
A12.3 A4α' L-Lys-Gly-D-Asp 10024, 11663
A12.4 A3α' L-Lys-L-Ser -
A21.1 A3β L-Orn-Gly2-3 3963, 3964, 3965, 3966, 11300, 11303, 12027, 20539, 20540, 20551
A21.2 A3β L-Orn(L-Lys)-L-Ala2-3 20092, 20094, 20095, 20099
A21.3 A3β L-Orn-L-Ser-L-Ala-L-Thr-L-Ala 20211, 20088, 20090, 20097, 20218, 20219
A21.4 A4β L-Orn-D-Asp 2266, 2528, 5837, 6123, 5965, 6307, 6350, 6351, 6352, 6353, 6354, 6355, 6356, 6357, 6362, 7084, 8475, 8476, 13279, 13345, 14784, 14785, 20049, 20052, 20055, 20109, 20391
A21.5 A4β L-Orn-D-Glu 7455, 9536, 9581, 10020, 10022, 10596, 20107, 20108, 20110, 20111, 20112, 20113, 20114, 20118, 20364, 20463, 20464
A21.6 A4β L-Orn(L-Lys)-D-Glu 7457, 20209, 20210, 20212
A21.7 A4β L-Orn-D-Ser-D-Asp 20215, 20239, 20456
A21.8 A4β L-Orn(L-Lys)-D-Ser-D-Asp 20082
A21.9 A4β L-Orn-L-Ser-D-Glu 20585, 20586
A21.10 A3β L-Orn-β-Ala 20745
A21.11 A5β L-Orn-L-Lys-D-Glu 6843, 6844, 9168, 10695
A21.12 A4β L-Orn-D-Ser-D-Glu 4813
A21.13 A4β L-Orn-Gly2-D-Glu 12335, 12336
A21.14 A4β L-Orn-L-Ala-Gly-D-Asp 12362
A22.1 A4β' L-Orn-D-Asp 20468
A23.1 A4β L-Orn-L-Glu; position 1 of the peptid subunit is L-Ser 13521
A31 A1γ meso-Dpm-directb 2150, 2872, 2648, 2950, 3953, 4712, 4749, 4847, 4848, 4849, 4902, 5007, 5008, 5970, 5971, 5972, 5973, 6306, 6344, 6688, 6922, 7069, 7109, 7110, 7111, 7198, 7199, 7200, 7201, 7487, 8801, 8802, 8821, 9583, 9584, 9585, 9586, 9657, 9658, 9659, 10641, 10667, 10718, 11140, 11141, 12028, 12331, 12332, 12890, 13192, 13024, 13675, 13193, 13657, 13814, 13876, 13953, 14060, 14184, 14451, 20199, 20205, 20128, 20131, 20132, 20137, 20147, 20148, 20150, 20151, 20156, 20158, 20159, 20162, 20163, 20165, 20314, 20170, 20171, 20174, 20246, 20270, 20271, 20294, 20295, 20296, 20297, 20298, 20300, 20301, 20302, 20305, 20306, 20307, 20342, 20344, 20348, 20536, 20537, 20403, 20404, 20405, 20406, 20408, 20411, 20412, 20415, 20425, 20426, 20444, 20455, 20460, 20461, 20462, 20465, 20466, 20467, 20483, 20504, 20505, 20506, 20507, 20508, 20509, 20510, 20511, 20649, 20651, 20657, 20658, 20659, 20660, 20521, 20524, 20582, 20583, 20589, 20590, 20596, 20599, 20600, 20601, 20623, 20624, 20625, 20626, 20632, 20634, 20635, 20668, 20678, 20722, 20730, 20731, 20735, 20739, 20748, 20750, 20751, 20755, 20756, 20757, 20759, 20760, 20761, 20762, 20763, 20764, 20765
A31.1 A4γ meso-Dpm-D-Glu2 9573, 9574
A31.2 A4γ meso-Dpm-D-Glu2; α-carboxyl group of D-Glu substituted by Gly 4810, 10240, 10241, 14564, 14566, 46339, 46341
A31.3 A4γ meso-Dpm-D-Asp-D-Glu; α-carboxyl group of D-Glu substituted by Gly 7083, 10672, 10673
A32.1 A1γ' meso-Dpm-direct -
A41.1 A3γ LL-Dpm-Gly 286, 300, 316, 1897, 3997, 4900, 4901, 8251, 8599, 10546, 10547, 10552, 12652, 12746, 13435, 20130, 20272, 20273, 20274, 20275, 20276, 20277, 20278, 20279, 20299, 20535, 20700, 20458, 20641
A41.2 A3γ LL-Dpm-Gly3; α-carboxyl group of D-Glu substituted by Gly 20308
A42.1 A3γ' LL-Dpm-Gly 10555, 11053, 12906, 12936, 43307
A51 A1δ Lan-direct 20482

 

Type B of cross-linkage

Nomenclature Peptidoglycan structures DSM No.
Schumann (2011) Schleifer and Kandler (1972)
B1 B1α {Gly} [L-Lys] D-Glu(Hyg)-Gly-L-Lysc 8607, 12509, 20140, 20172, 20427
B2 B1β {Gly} [L-Hse] D-Glu(Hyg)-Gly2-L-Lys 8600, 20530, 20754
B3 B1γ {Gly} [L-Glu] D-Glu(Hyg)-Gly2-L-Lys 20028
B4 B2α {L-Ser} [L-Orn] D-Glu-D-Lys(D-Orn) 20543, 20517
B5 B2β {Gly} [L-Hse] D-Glu-D-Orn 14013, 20129, 20135, 20141, 20149, 20542, 20527, 20528, 20529
B6 B2β {Gly} [L-Hse] D-Glu(Hyg)-Gly-D-Orn 8608, 8609, 8610, 8611, 12506, 12507, 12510, 12511, 12512, 12966, 13468, 14217, 20143, 20145, 20166, 20169, 20489, 20449, 20512, 20643, 20526, 20578, 20606, 20638
B7 B2γ {Gly} [L-Dab] D-Glu-D-Dab 340, 4854, 40, 7483, 7484, 7485, 7486, 7488, 8595, 8596, 8597, 8598, 13056, 13057, 14012, 14595, 14596, 14597, 15165, 15166, 15202, 20134, 20146, 20152, 20157, 20400, 20419, 20741, 46301, 46304, 46306, 46364
B8 B1β {Gly} [L-Hse] D-Glu-Gly-L-Dab 20154
B9 B2α {Gly} [L-Orn] D-Glu-D-Orn 8606, 11986, 11987
B10 B2β {Gly} [L-Hse] D-Glu-D-Dab 20618, 20619
B11 B2δ {Gly} [L-Ala] D-Glu-D-Dab-L-Thr 20621
B12 B2α {Gly} [L-Orn] D-Glu-Gly-D-Orn 20620
B13 B1δ {L-Ser} [L-Ala] D-Glu-L-Asp-L-Lys 12042
B14 B2β {Gly} [L-Hse] D-Glu-D-Lys 10309, 10310, 10311
B15 B1δ {L-Ser} [L-Ala] D-Glu-Gly-L-Lys-L-Lys 5055

 

a Extension by an apostrophe (e.g. A3α') denotes that the L-Ala residue found normally at position 1 of the peptide subunit in type A is replaced by Gly.

b Abbreviations: Dab, 2,4-diaminobutyric acid; Dpm, 2,6-diaminopimelic acid; Hse, homoserine; Hyg, threo-3-hydroxy-glutamic acid; Lan, lanthionine.

c { }, position 1; [ ], position 3.

Schleifer, K. H. & Kandler, O. (1972). Peptidoglycan types of bacterial cell walls and their taxonomic implications. Bacteriol Rev 36, 407-477.

Schumann, P. (2011). Peptidoglycan Structure. In Taxonomy of Prokaryotes, Methods in Microbiology, vol. 38, pp. 101-129. Edited by F. Rainey & A. Oren. London: Academic Press.