Nomenclature of Peptidoglycan Structures of Cross-Linkage Types A and B, with Examples of DSMZ Strains Having Specific Peptidoglycan Types

Type A of cross-linkage

NomenclaturePeptidoglycan structuresDSM No.
Schumann (2011)Schleifer and Kandler (1972)
A11A1αL-Lys-direct7447, 9682, 9683, 9684, 9849, 12492, 12643, 20066, 20311, 20379, 20340, 20341, 20393, 20395, 20627
A11.glyA1αL-Lys-direct; α-carboxyl group of D-Glu substituted by Gly-
A11.pepA2L-Lys peptide subunit1790, 1605, 2786, 14234, 20030, 46257
A11.1A3αL-Lys-Gly6203, 6208, 6209, 14480, 14481, 14482, 20213, 20089, 20091, 20121, 20416, 20431, 20446
A11.2A3αL-Lys-Gly5-64804, 4805, 4806, 4807, 4808, 4809, 6718, 7068, 7373, 7377, 14617, 20029, 20039, 20231, 20232, 20260, 20261, 20262, 20266, 20267, 20322, 20323, 20324, 20501, 20454, 20459, 20672, 20673, 20674, 20675, 20676, 20677, 20714, 20771
A11.3A3αL-Lys-Gly2-4-L-Ser1-2-Gly6717, 6732, 10656, 10657, 15096, 20036, 20037, 20038, 20042, 20044, 20316, 20359, 20373, 20228, 20229, 20263, 20264, 20265, 20325, 20326, 20327, 20328, 20329, 20330, 20597, 20608, 20609, 20610, 20723
A11.4A3αL-Lys-L-Ala9848, 13613, 20194, 20196, 20117, 20377, 20349, 20451, 20663, 20728, 20746
A11.5A3αL-Lys-L-Ala25636, 5576, 5577, 5578, 5623, 6634, 6777, 6905, 8249, 8581, 8582, 8583, 20186, 20188, 20189, 20192, 20202, 20375, 20288, 20392, 20545, 20399, 20662, 20523, 20560, 20561, 20563, 20564, 20565, 20567, 20568, 20569, 20572, 20573, 20575, 20725, 20727
A11.6A3αL-Lys-L-Ala3348, 2981, 11630, 11925, 11926, 12219, 20068, 20124, 20371, 20376, 20380, 20383, 20259, 20409, 20478, 20479, 20559, 20576, 46222
A11.7A3αL-Lys-L-Ala420032, 20033, 20319, 20320, 20321, 20447
A11.8A3αL-Lys-L-Ala-Gly4-59930, 9931, 20352, 20345
A11.9A3αL-Lys-L-Ala-L-Ala(L-Ser)7378, 20566, 20770
A11.10A3αL-Lys-L-Ala2-L-Ala(L-Ser)-
A11.11A3αL-Lys(L-Orn)-L-Ala2-L-Ser20220, 20222, 20224, 20438, 20439
A11.12A3αL-Lys-L-Ala2-Gly-L-Ala6783, 20064, 20385, 20684, 20685
A11.13A3αL-Lys-L-Ala-L-Ser20190, 20093, 20248, 20410
A11.14A3αL-Lys-L-Ser20102
A11.15A3αL-Lys-L-Ala2-L-Ser-
A11.16A3αL-Lys-L-Ala(L-Ser)-L-Ser20257
A11.17A3αL-Lys-L-Ala-L-Thr-L-Ala419, 420, 4983, 20115, 20116, 20126, 20138
A11.18A3αL-Lys-L-Ser-L-Ala20252, 20686
A11.19A3αL-Lys-L-Ser-L-Ser(L-Ala)20255
A11.20A3αL-Lys-L-Ser-L-Ala212221, 13734, 20014, 20187, 20193, 20200, 20240, 20241, 20484, 20343, 20346, 46216
A11.21A3αL-Lys(L-Orn)-L-Ala(L-Ser)-L-Ala26489, 6490, 6491, 10140, 20104, 20105, 20434, 20435
A11.22A3αL-Lys-L-Ser-L-Ala2-3; α-carboxyl group of D-Glu substituted by glycine amide20127
A11.23A3αL-Lys-L-Ser-L-Thr-L-Ala342, 12829, 13065, 13066, 20119, 20120, 20125, 20136, 20144, 20161, 20389, 20390, 20407
A11.24A3αL-Lys-L-Thr-Gly13760, 20061, 20067, 20386, 20715, 20716
A11.25A3αL-Lys-L-Thr-L-Ala20381, 20443, 20646, 20562, 20742
A11.26A3αL-Lys-L-Thr-L-Ala; α-carboxyl group of D-Glu substituted by alanine amide20142
A11.27A3αL-Lys-L-Thr-L-Ala25635, 13067, 20133
A11.28A3αL-Lys-L-Thr-L-Ala320153, 20550
A11.29A3αL-Lys-L-Thr-L-Ser(L-Ala)5199, 20062, 20065, 20480, 20558, 20574
A11.30A3αL-Lys-L-Thr-L-Ser-L-Ala2-
A11.31A4αL-Lys-D-Asp2094, 2146, 2381, 3320, 4747, 4838, 4839, 4840, 4841, 4864, 4865, 4866, 4903, 5632, 5633, 5634, 5661, 6035, 5622, 5705, 5707, 5708, 5731, 5732, 6630, 7370, 7371, 7372, 7374, 9126, 9172, 10177, 10550, 10551, 10532, 10533, 11492, 11664, 12361, 12744, 12745, 13145, 13335, 13343, 13344, 13989, 14526, 14421, 20001, 20003, 20004, 20005, 20006, 20007, 20008, 20010, 20011, 20012, 20015, 20016, 20017, 20019, 20020, 20021, 20022, 20023, 20051, 20053, 20181, 20182, 20184, 20197, 20203, 20206, 20207, 20214, 20054, 20056, 20057, 20059, 20063, 20069, 20072, 20073, 20074, 20075, 20076, 20077, 20079, 20080, 20081, 20087, 20096, 20098, 20100, 20101, 20160, 20312, 20315, 20318, 20175, 20176, 20177, 20178, 20180, 20216, 20353, 20354, 20355, 20356, 20357, 20382, 20384, 20225, 20238, 20242, 20243, 20244, 20245, 20247, 20249, 20250, 20253, 20254, 20258, 20280, 20281, 20283, 20284, 20285, 20287, 20289, 20291, 20293, 20331, 20332, 20333, 20334, 20335, 20336, 20337, 20338, 20485, 20486, 20487, 20492, 20494, 20495, 20496, 20497, 20498, 20499, 20339, 20350, 20351, 20388, 20533, 20534, 20433, 20450, 20452, 20453, 20469, 20475, 20477, 20481, 20642, 20653, 20654, 20655, 20515, 20531, 20532, 20552, 20553, 20554, 20555, 20556, 20557, 20570, 20571, 20580, 20584, 20587, 20588, 20602, 20605, 20607, 20628, 20633, 20670, 20679, 20680, 20681, 20682, 20690, 20691, 20692, 20717, 20718, 20719, 20720, 20721, 20726, 20749
A11.32A4αL-Lys(L-Orn)-D-Asp6492, 6493, 6494, 6531, 6532, 6533, 10105, 10106, 20083, 20084, 20086, 20221, 20436
A11.33A4αL-Lys-D-Glu7454, 13280, 14506, 14507, 14504, 14505, 20549, 20581, 20747
A11.34A4αL-Lys-L-Ala-D-Asp-
A11.35A4αL-Lys-L-Ala-L-Glu4640, 13068, 13069, 20122, 20123, 20168, 20413, 20647, 20648, 20579
A11.36A4αL-Lys-L-Ser-D-Asp11295
A11.37A4αL-Lys-D-Ser-D-Asp20106, 20155, 20424, 46215
A11.38A4αL-Lys-D-Ser-D-Glu20432
A11.39A4αL-Lys-L-Ser2-D-Glu20448
A11.40A4αL-Lys-Gly-D-Glu320, 2306, 2307, 14442
A11.41A3αL-Lys-Gly-L-Ala314508
A11.42A4αL-Lys-Gly-D-Asp6633, 20183
A11.43A4αL-Lys-D-Glu213884, 20317, 20547
A11.44A3αL-Lys-Gly(L-Ser)20445
A11.45A4αL-Lys-L-Thr-D-Asp20577
A11.46A3αL-Lys-L-Ala-Gly-L-Ala220593
A11.47A3αL-Lys-L-Ala-Gly; α-carboxyl group of D-Glu substituted by alanine amide20767
A11.48A4αL-Lys-L-Ser-D-Glu10543, 10542, 12657, 20603
A11.49A3αL-Lys-L-Ser-Gly20622
A11.50A3αL-Lys-L-Ala-Gly6778
A11.51A5αL-Lys-L-Lys-D-Glu8576, 8577, 11076, 11077, 11078, 13483, 20595
A11.52A5αL-Lys-L-Lys-D-Asp43320
A11.53A5αL-Lys-L-Ala-L-Lys-D-Glu9151, 9152, 9153, 20594, 20630, 20639
A11.54A4αL-Lys-L-Glu12333, 12334, 14418, 14419, 20167, 20645
A11.55A5αL-Lys(L-Orn)-L-Lys-D-Glu9169
A11.56A4αL-Lys-Gly-L-Glu6686, 6687, 6723, 20541
A11.57A4αL-Lys-L-Thr-D-Glu14281, 43852, 46000, 46001, 46097
A11.58A4αL-Lys-L-Ser-L-Glu10493, 10494
A11.59A4αL-Lys-L-Ala-D-Glu-
A11.60A4αL-Lys-D-Asp; α-carboxyl group of D-Glu substituted by glycine10495, 14235
A11.61A3αL-Lys-L-Ala(L-Ser)12493
A11.62A3αL-Lys-L-Ala2-Gly2-3-L-Ala(Gly)13988
A11.63A3αL-Lys-L-Ala-Gly3, L-Ser0-1-
A12.1A3α'aL-Lys-Gly20362, 20369, 20470, 20472
A12.2A4α'L-Lys-D-Glu7456, 20358, 20548, 20473
A12.3A4α'L-Lys-Gly-D-Asp10024, 11663
A12.4A3α'L-Lys-L-Ser-
A21.1A3βL-Orn-Gly2-33963, 3964, 3965, 3966, 11300, 11303, 12027, 20539, 20540, 20551
A21.2A3βL-Orn(L-Lys)-L-Ala2-320092, 20094, 20095, 20099
A21.3A3βL-Orn-L-Ser-L-Ala-L-Thr-L-Ala20211, 20088, 20090, 20097, 20218, 20219
A21.4A4βL-Orn-D-Asp2266, 2528, 5837, 6123, 5965, 6307, 6350, 6351, 6352, 6353, 6354, 6355, 6356, 6357, 6362, 7084, 8475, 8476, 13279, 13345, 14784, 14785, 20049, 20052, 20055, 20109, 20391
A21.5A4βL-Orn-D-Glu7455, 9536, 9581, 10020, 10022, 10596, 20107, 20108, 20110, 20111, 20112, 20113, 20114, 20118, 20364, 20463, 20464
A21.6A4βL-Orn(L-Lys)-D-Glu7457, 20209, 20210, 20212
A21.7A4βL-Orn-D-Ser-D-Asp20215, 20239, 20456
A21.8A4βL-Orn(L-Lys)-D-Ser-D-Asp20082
A21.9A4βL-Orn-L-Ser-D-Glu20585, 20586
A21.10A3βL-Orn-β-Ala20745
A21.11A5βL-Orn-L-Lys-D-Glu6843, 6844, 9168, 10695
A21.12A4βL-Orn-D-Ser-D-Glu4813
A21.13A4βL-Orn-Gly2-D-Glu12335, 12336
A21.14A4βL-Orn-L-Ala-Gly-D-Asp12362
A22.1A4β'L-Orn-D-Asp20468
A23.1A4βL-Orn-L-Glu; position 1 of the peptid subunit is L-Ser13521
A31A1γmeso-Dpm-directb2150, 2872, 2648, 2950, 3953, 4712, 4749, 4847, 4848, 4849, 4902, 5007, 5008, 5970, 5971, 5972, 5973, 6306, 6344, 6688, 6922, 7069, 7109, 7110, 7111, 7198, 7199, 7200, 7201, 7487, 8801, 8802, 8821, 9583, 9584, 9585, 9586, 9657, 9658, 9659, 10641, 10667, 10718, 11140, 11141, 12028, 12331, 12332, 12890, 13192, 13024, 13675, 13193, 13657, 13814, 13876, 13953, 14060, 14184, 14451, 20199, 20205, 20128, 20131, 20132, 20137, 20147, 20148, 20150, 20151, 20156, 20158, 20159, 20162, 20163, 20165, 20314, 20170, 20171, 20174, 20246, 20270, 20271, 20294, 20295, 20296, 20297, 20298, 20300, 20301, 20302, 20305, 20306, 20307, 20342, 20344, 20348, 20536, 20537, 20403, 20404, 20405, 20406, 20408, 20411, 20412, 20415, 20425, 20426, 20444, 20455, 20460, 20461, 20462, 20465, 20466, 20467, 20483, 20504, 20505, 20506, 20507, 20508, 20509, 20510, 20511, 20649, 20651, 20657, 20658, 20659, 20660, 20521, 20524, 20582, 20583, 20589, 20590, 20596, 20599, 20600, 20601, 20623, 20624, 20625, 20626, 20632, 20634, 20635, 20668, 20678, 20722, 20730, 20731, 20735, 20739, 20748, 20750, 20751, 20755, 20756, 20757, 20759, 20760, 20761, 20762, 20763, 20764, 20765
A31.1A4γmeso-Dpm-D-Glu29573, 9574
A31.2A4γmeso-Dpm-D-Glu2; α-carboxyl group of D-Glu substituted by Gly4810, 10240, 10241, 14564, 14566, 46339, 46341
A31.3A4γmeso-Dpm-D-Asp-D-Glu; α-carboxyl group of D-Glu substituted by Gly7083, 10672, 10673
A32.1A1γ'meso-Dpm-direct-
A41.1A3γLL-Dpm-Gly286, 300, 316, 1897, 3997, 4900, 4901, 8251, 8599, 10546, 10547, 10552, 12652, 12746, 13435, 20130, 20272, 20273, 20274, 20275, 20276, 20277, 20278, 20279, 20299, 20535, 20700, 20458, 20641
A41.2A3γLL-Dpm-Gly3; α-carboxyl group of D-Glu substituted by Gly20308
A42.1A3γ'LL-Dpm-Gly10555, 11053, 12906, 12936, 43307
A51A1δLan-direct20482

 

Type B of cross-linkage

NomenclaturePeptidoglycan structuresDSM No.
Schumann (2011) Schleifer and Kandler (1972)
B1B1α{Gly} [L-Lys] D-Glu(Hyg)-Gly-L-Lysc8607, 12509, 20140, 20172, 20427
B2B1β{Gly} [L-Hse] D-Glu(Hyg)-Gly2-L-Lys8600, 20530, 20754
B3B1γ{Gly} [L-Glu] D-Glu(Hyg)-Gly2-L-Lys20028
B4B2α{L-Ser} [L-Orn] D-Glu-D-Lys(D-Orn)20543, 20517
B5B2β{Gly} [L-Hse] D-Glu-D-Orn14013, 20129, 20135, 20141, 20149, 20542, 20527, 20528, 20529
B6B2β{Gly} [L-Hse] D-Glu(Hyg)-Gly-D-Orn8608, 8609, 8610, 8611, 12506, 12507, 12510, 12511, 12512, 12966, 13468, 14217, 20143, 20145, 20166, 20169, 20489, 20449, 20512, 20643, 20526, 20578, 20606, 20638
B7B2γ{Gly} [L-Dab] D-Glu-D-Dab340, 4854, 40, 7483, 7484, 7485, 7486, 7488, 8595, 8596, 8597, 8598, 13056, 13057, 14012, 14595, 14596, 14597, 15165, 15166, 15202, 20134, 20146, 20152, 20157, 20400, 20419, 20741, 46301, 46304, 46306, 46364
B8B1β{Gly} [L-Hse] D-Glu-Gly-L-Dab20154
B9B2α{Gly} [L-Orn] D-Glu-D-Orn8606, 11986, 11987
B10B2β{Gly} [L-Hse] D-Glu-D-Dab20618, 20619
B11B2δ{Gly} [L-Ala] D-Glu-D-Dab-L-Thr20621
B12B2α{Gly} [L-Orn] D-Glu-Gly-D-Orn20620
B13B1δ{L-Ser} [L-Ala] D-Glu-L-Asp-L-Lys12042
B14B2β{Gly} [L-Hse] D-Glu-D-Lys10309, 10310, 10311
B15B1δ{L-Ser} [L-Ala] D-Glu-Gly-L-Lys-L-Lys5055

 

a Extension by an apostrophe (e.g. A3α') denotes that the L-Ala residue found normally at position 1 of the peptide subunit in type A is replaced by Gly.

b Abbreviations: Dab, 2,4-diaminobutyric acid; Dpm, 2,6-diaminopimelic acid; Hse, homoserine; Hyg, threo-3-hydroxy-glutamic acid; Lan, lanthionine.

c{ }, position 1; [ ], position 3.

Schleifer, K. H. & Kandler, O. (1972). Peptidoglycan types of bacterial cell walls and their taxonomic implications. Bacteriol Rev 36, 407-477.

Schumann, P. (2011). Peptidoglycan Structure. In Taxonomy of Prokaryotes, Methods in Microbiology, vol. 38, pp. 101-129. Edited by F. Rainey & A. Oren. London: Academic Press.