Stem cell models

The research of the group “Stem cell models” focuses on the development of cellular models to understand human imprinting diseases and the development of tumors of the eye, retinoblastoma and uveal melanoma. We use human cell lines and human pluripotent stem cells (induced and embryonic) to establish such models and we employ differentiation of these cells and molecular biology techniques, like genome editing and next generation sequencing, for analysis.