COI barcoding for verfication of animal cell lines
The DSMZ offers the service of verification of animal cell lines to external customers based on COI barcoding.
Use of false animal cell lines due to insufficient verification of species-specific models contributes to irreproducibility of data from studies based on animal cell lines an in the end unsuccessful translation between species (mouse/human)
COI barcoding is based on isolation of mitochondrial DNA, PCR amplification of Cytochrome C Oxidase I (COI) gene, direct amplicon sequencing and DNA sequence comparison (DNA barcoding). DNA barcodes are now available for numerous taxa, including all species of insects, fish, amphibia, birds and mammals.
To order a cell line authentication services please contact mutz(at)dsmz.de. We will then send you the current submission form.
For pricing, please refer to our price list.
For technical questions please use our contact form.