DZIF Group "Microbial Genome Research"
Prof. Dr. Ulrich Nübel
DZIF-Professorship and Group "Microbial Genome Research"
Leibniz Institute DSMZ-German Collection of Microrganisms and Cell Cultures
Inhoffenstrasse 7 B
tel: 0531 -2616-390
Population genomics and phylogeography. Our mission is to understand the evolution and spatial dispersal of bacterial populations, with a focus on drug resistance and secondary metabolite biosynthesis.
Genome-based molecular epidemiology. We trace the emergence and transmission of bacterial pathogens at high spatial and temporal resolution based on large-scale bacterial whole-genome sequence analyses. We develop sequence-based tools for early detection of outbreaks of infections in healthcare-associated settings (EU-funded project COMPARE) and we investigate major spreading routes and reservoirs of the pathogen Clostridium difficile (project CDiff).
Functional genomics of novel microbial producers. Prokaryotes represent an enormously diverse potential resource for novel bio-active compounds. We seek to accelerate natural product discovery by using high-throughput genome sequencing and genome mining to identify novel producer organisms outside of commonly studied bacterial groups (DZIF).